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对先前接受联合化疗的晚期卵巢癌患者采用全腹照射进行挽救性治疗。

Salvage therapy with whole-abdominal irradiation in patients with advanced carcinoma of the ovary previously treated by combination chemotherapy.

作者信息

Peters W A, Blasko J C, Bagley C M, Rudolph R H, Smith M R, Rivkin S E

出版信息

Cancer. 1986 Aug 15;58(4):880-2. doi: 10.1002/1097-0142(19860815)58:4<880::aid-cncr2820580413>3.0.co;2-z.

DOI:10.1002/1097-0142(19860815)58:4<880::aid-cncr2820580413>3.0.co;2-z
PMID:3719555
Abstract

Whole-abdominal irradiation was delivered to 22 patients with epithelial carcinoma of the ovary who had persistent disease after chemotherapy. Seventeen patients were treated with an open whole-abdominal field and 5 with the moving-field technique. Eleven of the 22 also received a pelvic boost. Two of nine patients with microscopic disease at second look are alive and disease-free at 34 and 52 months, respectively. There were no salvages among the patient with macroscopic disease. Major complications included bowel obstruction in three patients and radiation enteritis in one patient. Whole-abdominal irradiation is not an effective salvage regimen after multiagent chemotherapy.

摘要

对22例化疗后仍有持续性疾病的卵巢上皮癌患者进行了全腹照射。17例患者采用开放全腹野治疗,5例采用移动野技术治疗。22例患者中有11例还接受了盆腔加强照射。9例二次探查有微小病灶的患者中,分别有2例在34个月和52个月时存活且无疾病。有肉眼可见病灶的患者无一挽救成功。主要并发症包括3例肠梗阻和1例放射性肠炎。多药化疗后,全腹照射不是一种有效的挽救方案。

相似文献

1
Salvage therapy with whole-abdominal irradiation in patients with advanced carcinoma of the ovary previously treated by combination chemotherapy.对先前接受联合化疗的晚期卵巢癌患者采用全腹照射进行挽救性治疗。
Cancer. 1986 Aug 15;58(4):880-2. doi: 10.1002/1097-0142(19860815)58:4<880::aid-cncr2820580413>3.0.co;2-z.
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Whole-abdomen radiation as a second-line therapy for epithelial ovarian cancer.
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Whole abdominal radiotherapy following second-look laparotomy for ovarian carcinoma.卵巢癌二次剖腹探查术后的全腹放疗。
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Twice-daily, split-course abdominopelvic radiation therapy after chemotherapy and positive second-look laparotomy for epithelial ovarian carcinoma.上皮性卵巢癌化疗及二次剖腹探查术结果阳性后,每日两次的分割疗程腹盆腔放射治疗。
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引用本文的文献

1
Radiation Treatment in Women with Ovarian Cancer: Past, Present, and Future.卵巢癌女性的放射治疗:过去、现在与未来
Front Oncol. 2017 Aug 21;7:177. doi: 10.3389/fonc.2017.00177. eCollection 2017.