Peters W A, Blasko J C, Bagley C M, Rudolph R H, Smith M R, Rivkin S E
Cancer. 1986 Aug 15;58(4):880-2. doi: 10.1002/1097-0142(19860815)58:4<880::aid-cncr2820580413>3.0.co;2-z.
Whole-abdominal irradiation was delivered to 22 patients with epithelial carcinoma of the ovary who had persistent disease after chemotherapy. Seventeen patients were treated with an open whole-abdominal field and 5 with the moving-field technique. Eleven of the 22 also received a pelvic boost. Two of nine patients with microscopic disease at second look are alive and disease-free at 34 and 52 months, respectively. There were no salvages among the patient with macroscopic disease. Major complications included bowel obstruction in three patients and radiation enteritis in one patient. Whole-abdominal irradiation is not an effective salvage regimen after multiagent chemotherapy.
对22例化疗后仍有持续性疾病的卵巢上皮癌患者进行了全腹照射。17例患者采用开放全腹野治疗,5例采用移动野技术治疗。22例患者中有11例还接受了盆腔加强照射。9例二次探查有微小病灶的患者中,分别有2例在34个月和52个月时存活且无疾病。有肉眼可见病灶的患者无一挽救成功。主要并发症包括3例肠梗阻和1例放射性肠炎。多药化疗后,全腹照射不是一种有效的挽救方案。