School of Pharmacy, Lanzhou University, Lanzhou, China.
Oncology Center, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Phytother Res. 2023 Jul;37(7):3135-3160. doi: 10.1002/ptr.7869. Epub 2023 May 17.
Glycyrrhizae Radix et Rhizoma is a well-known herbal medicine with a wide range of pharmacological functions that has been used throughout Chinese history. This review presents a comprehensive introduction to this herb and its classical prescriptions. The article discusses the resources and distribution of species, methods of authentication and determination chemical composition, quality control of the original plants and herbal medicines, dosages use, common classical prescriptions, indications, and relevant mechanisms of the active content. Pharmacokinetic parameters, toxicity tests, clinical trials, and patent applications are discussed. The review will provide a good starting point for the research and development of classical prescriptions to develop herbal medicines for clinical use.
甘草是一种广为人知的草药，具有广泛的药理作用，在中国历史上一直被使用。本综述对该草药及其经典方剂进行了全面介绍。文章讨论了该物种的资源和分布、鉴定和测定化学成分的方法、原植物和草药的质量控制、剂量使用、常见经典方剂、适应证以及有效成分的相关机制。讨论了药代动力学参数、毒性试验、临床试验和专利申请。该综述将为经典方剂的研究和开发提供一个良好的起点，以开发用于临床的草药。
