Jeyasri Rajendran, Muthuramalingam Pandiyan, Karthick Kannan, Shin Hyunsuk, Choi Sung Hwan, Ramesh Manikandan
Department of Biotechnology, Alagappa University, Science Campus, Karaikudi, Tamil Nadu 630 003 India.
Division of Horticultural Science, College of Agriculture and Life Sciences, Gyeongsang National University, Jinju, 52725 South Korea.
Plant Cell Tissue Organ Cult. 2023;153(3):447-458. doi: 10.1007/s11240-023-02485-8. Epub 2023 Mar 20.
Plant secondary metabolites are bioactive scaffolds that are crucial for plant survival in the environment and to maintain a defense mechanism from predators. These compounds are generally present in plants at a minimal level and interestingly, they are found to have a wide variety of therapeutic values for humans. Several medicinal plants are used for pharmaceutical purposes due to their affordability, fewer adverse effects, and vital role in traditional remedies. Owing to this reason, these plants are exploited at a high range worldwide and therefore many medicinal plants are on the threatened list. There is a need of the hour to tackle this major problem, one effective approach called elicitation can be used to enhance the level of existing and novel plant bioactive compounds using different types of elicitors namely biotic and abiotic. This process can be generally achieved by and experiments. The current comprehensive review provides an overview of biotic and abiotic elicitation strategies used in medicinal plants, as well as their effects on secondary metabolites enhancement. Further, this review mainly deals with the enhancement of biomass and biosynthesis of different bioactive compounds by methyl jasmonate (MeJA) and salicylic acid (SA) as elicitors of wide medicinal plants in by using different cultures. The present review was suggested as a significant groundwork for peers working with medicinal plants by applying elicitation strategies along with advanced biotechnological approaches.
植物次生代谢产物是具有生物活性的支架，对于植物在环境中的生存以及维持抵御捕食者的防御机制至关重要。这些化合物在植物中通常含量极低，有趣的是，它们对人类具有广泛的治疗价值。一些药用植物因其价格低廉、副作用少以及在传统疗法中的重要作用而被用于制药目的。由于这个原因，这些植物在全球范围内被大量开发，因此许多药用植物都在濒危名单上。当下迫切需要解决这个重大问题，一种有效的方法即诱导，可以利用不同类型的诱导剂（生物诱导剂和非生物诱导剂）来提高现有和新型植物生物活性化合物的水平。这个过程通常可以通过 和 实验来实现。当前的综合综述概述了药用植物中使用的生物和非生物诱导策略，以及它们对次生代谢产物增强的影响。此外，本综述主要探讨了通过使用不同培养方式，以茉莉酸甲酯（MeJA）和水杨酸（SA）作为广泛药用植物的诱导剂，对不同生物活性化合物的生物量和生物合成的增强作用。本综述被认为是为从事药用植物研究的同行提供的一项重要基础工作，通过应用诱导策略以及先进的生物技术方法。
