Terminal deoxynucleotidyl transferase as a leukemic marker in bone marrow transplant recipients.

Terminal deoxynucleotidyl transferase was measured in bone marrow samples from five patients with acute lymphoblastic leukemia in relapse before bone marrow transplantation and serially thereafter. This enzyme seems to be a sensitive marker which can serve as an early indicator of recurrence of the disease. It is not influenced by clinical graft-versus-host reaction.