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[深度学习图像重建在提高双低剂量CT肺血管造影图像质量及评估Qanadli栓塞指数中的应用价值]

[The application value of deep learning image reconstruction on improving image quality and evaluating the Qanadli embolism index of dual low-dose CT pulmonary angiography].

作者信息

Qiu S M, Zhang H, Liu Z X, Zhang L, Meng Y K, Sun X N, Xie L X, Zhang Y C, Wang H, Xu K

机构信息

Department of Radiology, the Affiliated Hospital of Xuzhou Medical University, Xuzhou 221002, China.

Department of Radiology, Suining Hospital Affiliated of Xuzhou Medical University, Xuzhou 221200, China.

出版信息

Zhonghua Yi Xue Za Zhi. 2023 May 23;103(19):1477-1482. doi: 10.3760/cma.j.cn112137-20230313-00392.

Abstract

To compare the image quality and Qanadli embolism index between deep learning image reconstruction (DLR) and adaptive statistical iterative reconstruction-veo (ASiR-V) in dual low-dose CT pulmonary angiography (CTPA) with low contrast agent dose and low radiation dose. Eighty-eight patients who underwent dual low-dose CTPA in the radiology department of the affiliated hospital of Xuzhou Medical University from October 2020 to March 2021 were retrospectively analyzed, including 44 males and 44 females, aged from 11 to 87 years (61±15 years). The CTPA examination were performed using 80 kV tube voltage and 20 ml contrast agent. The raw data were reconstructed using standard kernel DLR high level (DL-H) and ASiR-V reconstruction, respectively. The patients were divided into standard kernel DL-H group (=88, 33 cases of positive embolism) and ASiR-V group (=88, 36 cases of positive embolism). The CT value, image noise, signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), subjective image quality score, Qanadli embolism index, positive rate and positive Qanadli embolism index were compared between the two groups. There were no statistically significant differences in CT values of the main pulmonary artery, the right pulmonary artery and the left pulmonary artery between the standard kernel DL-H group and ASiR-V group [(405.8±111.7) vs (404.0±112.0) HU, (412.9±113.1) vs (411.5±112.2) HU, (418.1±119.9) vs (415.4±118.0) HU, respectively;all >0.05)]. The image noise of the main pulmonary artery, the right pulmonary artery and the left pulmonary artery in the standard kernel DL-H group was significantly lower than the ASiR-V group(16.6±4.7 vs 28.1±4.8, 18.3±6.1 vs 29.8±4.9, 17.6±5.6 vs 28.4±4.7, respectively;all <0.001). The SNR and CNR of the main pulmonary artery, the right pulmonary artery and the left pulmonary artery in the standard kernel DL-H group were significantly higher than the ASiR-V group(SNR: 25.5±7.1 vs 14.5±3.9, 23.9±7.2 vs 13.9±3.4, 24.9±7.4 vs 14.8±4.1, CNR: 21.6±6.6 vs 12.3±3.9, 20.2±6.7 vs 11.8±3.4, 21.2±6.9 vs 12.6±4.1, respectively;all <0.001). The subjective image quality score of the standard kernel DL-H group was significantly higher than the ASiR-V group (4.6 vs 3.8, <0.001). There were no significant difference in the Qanadli embolism index, positive rate and positive Qanadli embolism index between the two groups (all >0.05). Compared with ASiR-V reconstruction algorithms group, standard kernel DL-H reconstruction algorithms can significantly improve the image quality of dual low-dose CTPA.

摘要

在低对比剂剂量和低辐射剂量的双源低剂量CT肺血管造影(CTPA)中,比较深度学习图像重建(DLR)与自适应统计迭代重建-veo(ASiR-V)之间的图像质量和Qanadli栓塞指数。回顾性分析2020年10月至2021年3月在徐州医科大学附属医院放射科接受双源低剂量CTPA检查的88例患者,其中男性44例,女性44例,年龄11至87岁(61±15岁)。CTPA检查采用80 kV管电压和20 ml对比剂。原始数据分别采用标准核DLR高级模式(DL-H)和ASiR-V重建。患者分为标准核DL-H组(n = 88,阳性栓塞33例)和ASiR-V组(n = 88,阳性栓塞36例)。比较两组的CT值、图像噪声、信噪比(SNR)、对比噪声比(CNR)、主观图像质量评分、Qanadli栓塞指数、阳性率及阳性Qanadli栓塞指数。标准核DL-H组与ASiR-V组主肺动脉、右肺动脉及左肺动脉的CT值比较,差异均无统计学意义[分别为(405.8±111.7) vs (404.0±112.0)HU、(412.9±113.1) vs (411.5±112.2)HU、(418.1±119.9) vs (415.4±118.0)HU;均P>0.05]。标准核DL-H组主肺动脉、右肺动脉及左肺动脉的图像噪声均显著低于ASiR-V组(分别为16.6±4.7 vs 28.1±4.8、18.3±6.1 vs 29.8±4.9、17.6±5.6 vs 28.4±4.7;均P<0.001)。标准核DL-H组主肺动脉、右肺动脉及左肺动脉的SNR和CNR均显著高于ASiR-V组(SNR:25.5±7.1 vs 14.5±3.9、23.9±7.2 vs 13.9±3.4、24.9±7.4 vs 14.8±4.1,CNR:21.6±6.6 vs 12.3±3.9、20.2±6.7 vs 11.8±3.4、21.2±6.9 vs 12.6±4.1;均P<0.001)。标准核DL-H组主观图像质量评分显著高于ASiR-V组(4.6 vs 3.8,P<0.001)。两组Qanadli栓塞指数、阳性率及阳性Qanadli栓塞指数比较,差异均无统计学意义(均P>0.05)。与ASiR-V重建算法组比较,标准核DL-H重建算法可显著提高双源低剂量CTPA的图像质量。

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