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在小牛和小鼠胸腺以及裸鼠发育不全胸腺中检测胸腺素5 。

Detection of thymosin 5 in calf and mouse thymus and in nude mouse dysgenetic thymus.

作者信息

Mándi B, Holub M, Rossmann P, Csaba B, Glant T, Olveti E

出版信息

Folia Biol (Praha). 1979;25(1):49-55.

PMID:371994
Abstract

Thymosin 5 was traced in calf and mouse thymuses by fluorochrome-labelled rabbit anti-calf thymosin. The presence of thymosin 5 or its individual components was found 1. in groups of cortical epithelial cells in calf thymuses and in single cortical epithelial cells in mouse thymuses. 2. In some marginal (blastema) cells of the thymus cortex of calves and 14-day-old mice. 3. In perivascular epithelial cells of the calf thymus. 4. In occasional medullary epithelial cells of the calf and mouse thymus. In all cases there was a marked alternation of entirely negative and positive cell-containing thymic lobuli. In 4 of 13 cases comparatively strong positivity was found in tightyly arranged epithelial cells in an individual acinus in the dysgenetic thymus of nude mice, the positive cases being concentrated among the youngest mice studied.

摘要

用荧光染料标记的兔抗小牛胸腺素对小牛和小鼠胸腺中的胸腺素5进行追踪。发现胸腺素5或其单个成分存在于:1. 小牛胸腺的皮质上皮细胞群以及小鼠胸腺的单个皮质上皮细胞中。2. 小牛和14日龄小鼠胸腺皮质的一些边缘(胚基)细胞中。3. 小牛胸腺的血管周围上皮细胞中。4. 小牛和小鼠胸腺偶尔出现的髓质上皮细胞中。在所有情况下,胸腺小叶中完全阴性和阳性细胞存在明显交替。在13例中的4例中,在裸鼠发育不全胸腺的单个腺泡中紧密排列的上皮细胞中发现了相对较强的阳性,阳性病例集中在研究的最年幼小鼠中。

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Detection of thymosin 5 in calf and mouse thymus and in nude mouse dysgenetic thymus.在小牛和小鼠胸腺以及裸鼠发育不全胸腺中检测胸腺素5 。
Folia Biol (Praha). 1979;25(1):49-55.
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引用本文的文献

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Identification of thymostimulin secreting cells in calf thymus by immunoperoxidase method.通过免疫过氧化物酶法鉴定小牛胸腺中分泌胸腺刺激素的细胞。
Histochemistry. 1984;80(3):207-11. doi: 10.1007/BF00495767.