胸腺素β4：大鼠和小鼠组织中一种普遍存在的肽。
Thymosin beta 4: a ubiquitous peptide in rat and mouse tissues.
作者信息
Hannappel E, Xu G J, Morgan J, Hempstead J, Horecker B L
出版信息
Proc Natl Acad Sci U S A. 1982 Apr;79(7):2172-5. doi: 10.1073/pnas.79.7.2172.
Abstract
Thymosin beta 4, recently isolated from calf thymus, is present in a number of rat and mouse tissues, including spleen, thymus, brain, lung, liver, and heart muscle. High concentrations are found in peritoneal macrophages, suggesting that its occurrence in other tissues may be related to the presence of macrophages or macrophage-like cells in these tissues. The conclusion that "thymosin" beta 4 does not originate solely in the thymus gland is supported by the high concentrations found in tissues of athymic (nu/nu) mice.
摘要
胸腺素β4最近从小牛胸腺中分离出来，存在于多种大鼠和小鼠组织中，包括脾脏、胸腺、脑、肺、肝和心肌。在腹膜巨噬细胞中发现高浓度，这表明它在其他组织中的存在可能与这些组织中巨噬细胞或巨噬细胞样细胞的存在有关。无胸腺（nu/nu）小鼠组织中发现的高浓度支持了“胸腺素”β4并非仅起源于胸腺的结论。
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