Ann Ital Chir. 2023 Apr 18;93:S2239253X23039385.
Ameloblastic carcinoma is a rare and aggressive malignant odontogenic tumour that can arise de novo or from a preexisting benign lesion. It most frequently involves the mandible, and its clinical course is aggressive with extensive local destruction. Although rare, these lesions have been known to metastasize, mostly to regional lymph nodes or lungs. Surgical therapy, eventually followed by radiotherapy, is the treatment modality most frequently used, while the role of chemotherapy remains unclear. Here we present a case of secondary ameloblastic carcinoma of the mandible in a 33-year-old male patient with typical aggressiveness and extensive local destruction and metastasis with a follow-up period of 93 months. KEY WORDS: Ameloblastic Carcinoma, Head and Neck Cancer, Maxillofacial Surgery, Oncological Surgery.
成釉细胞瘤是一种罕见且侵袭性强的恶性牙源性肿瘤，可由新生物或由先前存在的良性病变发展而来。它最常累及下颌骨，其临床病程具有侵袭性，广泛的局部破坏。尽管罕见，但这些病变已被证实会转移，主要转移到局部淋巴结或肺部。手术治疗，最终辅以放疗，是最常使用的治疗方式，而化疗的作用仍不清楚。本文报告了一例 33 岁男性患者下颌继发成釉细胞瘤，具有典型的侵袭性和广泛的局部破坏以及转移，随访时间为 93 个月。关键词：成釉细胞瘤、头颈部癌症、颌面外科、肿瘤外科学。
