多余der(22)、t(11;22)综合征中的先天性心脏病

Congenital heart disease in supernumerary der(22),t(11;22) syndrome.

作者信息

Lin A E, Bernar J, Chin A J, Sparkes R S, Emanuel B S, Zackai E H

出版信息

Clin Genet. 1986 Apr;29(4):269-75. doi: 10.1111/j.1399-0004.1986.tb01254.x.

DOI:10.1111/j.1399-0004.1986.tb01254.x

PMID:3720005

Abstract

Congenital heart disease occurred in 62% of the reported cases of supernumerary der(22) syndrome. These were most commonly acyanotic lesions such as atrial septal defect, ventricular septal defect or patent ductus arteriosus. Heart disease did not, however, appear to be a major determinant of survival.

摘要

在报告的额外der(22)综合征病例中，62%出现先天性心脏病。这些最常见的是非青紫型病变，如房间隔缺损、室间隔缺损或动脉导管未闭。然而，心脏病似乎不是生存的主要决定因素。