From the National Centre for Immunisation Research and Surveillance, New South Wales, Australia.
School of Public Health, Faculty of Medicine, The University of Sydney, New South Wales, Australia.
Pediatr Infect Dis J. 2023 Sep 1;42(9):e341-e342. doi: 10.1097/INF.0000000000003972. Epub 2023 May 18.
A global resurgence of invasive pneumococcal disease (IPD) has been noted in children. We provide a detailed clinical and epidemiological analysis of IPD in Australian children following relaxation of nonpharmaceutical interventions against coronavirus disease 2019, revealing significant morbidity and mortality-even in vaccinated children without known predisposing risk factors. Almost half of the IPD cases were caused by serotypes not covered by the 13-valent pneumococcal conjugate vaccine.
全球侵袭性肺炎球菌病（IPD）在儿童中再次出现。我们详细分析了澳大利亚儿童在放松针对 2019 年冠状病毒病的非药物干预措施后的 IPD 情况，结果显示即使是接种疫苗且无已知易感危险因素的儿童，发病率和死亡率仍很高。几乎一半的 IPD 病例是由 13 价肺炎球菌结合疫苗未覆盖的血清型引起的。
