Schenker Rachel B, Dybbro Eric, Kim Brian, Patel Shreena, Yanni George
From the Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Children's Hospital, Los Angeles.
Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Phoenix Children's Hospital.
JPGN Rep. 2023 Apr 18;4(2):e311. doi: 10.1097/PG9.0000000000000311. eCollection 2023 May.
Alcohol-associated hepatitis (AH) refers to liver injury from alcoholic intake that usually occurs after years of heavy alcohol abuse. Frequent, heavy alcohol consumption causes hepatic inflammation, fibrosis, and cirrhosis. Some patients develop severe AH, which carries high short-term mortality and is the second most common reason for adult liver transplants (LTs) worldwide. We present one of the first cases of a teenager diagnosed with severe AH that led to LT evaluation. Our patient was a 15-year-old male who presented with epistaxis and 1 month of jaundice after 3 years of heavy daily alcohol abuse. In collaboration with our adult transplant hepatologist colleagues, we initiated a management plan that consisted of treating acute alcohol withdrawal, steroid utilization, mental health support, and LT evaluation.
酒精性肝炎（AH）是指因饮酒导致的肝损伤，通常发生在多年大量酗酒之后。频繁、大量饮酒会引发肝脏炎症、纤维化和肝硬化。一些患者会发展为严重的酒精性肝炎，其短期死亡率很高，是全球成人肝移植（LT）的第二大常见原因。我们报告了首例被诊断为严重酒精性肝炎并因此接受肝移植评估的青少年病例。我们的患者是一名15岁男性，在每天大量酗酒3年后出现鼻出血和1个月的黄疸症状。我们与成人移植肝病专家同事合作，启动了一项管理计划，包括治疗急性酒精戒断、使用类固醇、提供心理健康支持以及进行肝移植评估。
