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早期玻璃体切除术:白内障手术后急性眼内炎的有效治疗方法

Early Vitrectomy: An Effective Treatment for Acute Postcataract Surgery Endophthalmitis.

作者信息

Najafabadi Farhad Fazel, Salehi Ali, Vaezi Mohammad Hadi, Ghanbari Heshmatollah, Najafabadi Mohamadreza Fazel, Koosha Nima, Jafarzadeh Zahra

机构信息

Department of Ophthalmology, Isfahan Eye Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.

Department of Ophthalmology, Shahrekord University of Medical Sciences, Shahr-e Kord, Iran.

出版信息

Adv Biomed Res. 2023 Mar 28;12:79. doi: 10.4103/abr.abr_44_21. eCollection 2023.

Abstract

BACKGROUND

Endophthalmitis is a rare but a high morbid complication after cataract surgery, and a gold standard treatment is not recommended yet. In this study, we aim to evaluate the effect of early vitrectomy on the visual acuity of patients with postcataract endophthalmitis.

MATERIALS AND METHODS

This study was a single-arm clinical trial on 27 patients with postcataract surgery endophthalmitis. Early vitrectomy was the intervention. Visual acuity as the primary outcome was evaluated and compared at baseline, at discharge, and 1 and 3 months after the intervention.

RESULTS

From 27 patients who included in our study, six patients gain favorable visual acuity of 5/10 and above (success rate = 22%), and four of them have no improvement in their visual acuity. Retinal detachment was reported as a complication in just one case. Negative culture was a predictor for success in terms of visual acuity after the surgery. All patients who gain favorable results, presented in the first 15 days after the cataract surgery.

CONCLUSION

The result of our study showed that, considering complete, early vitrectomy for the treatment of postcataract surgery endophthalmitis, especially for those who presented in the first 15 days of cataract surgery and for those who have negative culture is promising.

摘要

背景

眼内炎是白内障手术后一种罕见但高致残的并发症,目前尚无推荐的金标准治疗方法。在本研究中,我们旨在评估早期玻璃体切除术对白内障术后眼内炎患者视力的影响。

材料与方法

本研究是一项针对27例白内障手术后眼内炎患者的单臂临床试验。干预措施为早期玻璃体切除术。以视力作为主要结局指标,在基线、出院时以及干预后1个月和3个月进行评估和比较。

结果

在纳入我们研究的27例患者中,6例患者获得了5/10及以上的良好视力(成功率=22%),其中4例患者视力无改善。仅1例报告有视网膜脱离并发症。术后培养结果为阴性是视力成功恢复的一个预测因素。所有获得良好结果的患者均在白内障手术后的前15天内出现。

结论

我们的研究结果表明,对于白内障手术后眼内炎的治疗,尤其是对于那些在白内障手术后前15天内出现且培养结果为阴性的患者,考虑进行早期玻璃体切除术是有前景的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8dc6/10186043/937f2df38bb0/ABR-12-79-g001.jpg

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