Strømme Sofie Hammernes, Guddal Maren Hjelle, Fenstad Anne Marie, Visnes Håvard, Zwart John-Anker, Storheim Kjersti, Johnsen Marianne Bakke
Department of Rehabilitation Science and Health Technology, Oslo Metropolitan University, Oslo, Norway.
Department of Research and Innovation, Oslo University Hospital, Oslo, Norway.
BMJ Open Sport Exerc Med. 2023 May 15;9(2):e001453. doi: 10.1136/bmjsem-2022-001453. eCollection 2023.
The purpose of this study was to investigate whether self-reported musculoskeletal pain (MSP) was associated with a future anterior cruciate ligament reconstruction (ACLR).
In this population-based prospective cohort study, we included 8087 participants from the adolescent part of the Trøndelag Health Study (Young-HUNT) in Norway. The exposure was self-reported MSP from the Young-HUNT3 study (2006-2008), which was categorised into two MSP load groups (high MSP and low MSP) based on frequency and number of pain sites. The outcome was ACLRs recorded in the Norwegian Knee Ligament Register between 2006 and 2019. Logistic regression was used to investigate association between MSP load and ACLR, given as ORs with 95% CIs. All tests were two-sided and p values of ≤0.05 were considered statistically significant.
8087 adolescents were included. We identified a total of 99 ACLRs, with 6 ACLRs (0.9%) in adolescents who reported high MSP load and 93 ACLRs (1.3%) among those who reported low MSP load. Adolescents reporting high MSP load had 23% lower odds of an ACLR (OR 0.77, 95% CI 0.31 to 1.91) compared with adolescents with low MSP load. However, the CIs were very wide.
Self-reported high MSP load in adolescents was not associated with increased risk of future ACLR. Although the number of participants was high, the relatively few cases of ACLR mean that we cannot be conclusive about the presence or absence of an association.
本研究旨在调查自我报告的肌肉骨骼疼痛（MSP）是否与未来的前交叉韧带重建（ACLR）相关。
在这项基于人群的前瞻性队列研究中，我们纳入了来自挪威特隆赫姆郡健康研究（Young-HUNT）青少年部分的8087名参与者。暴露因素为来自Young-HUNT3研究（2006 - 2008年）中自我报告的MSP，根据疼痛部位的频率和数量分为两个MSP负荷组（高MSP和低MSP）。结局为2006年至2019年挪威膝关节韧带登记处记录的ACLR。采用逻辑回归分析来研究MSP负荷与ACLR之间的关联，以比值比（OR）及95%置信区间（CI）表示。所有检验均为双侧检验，p值≤0.05被认为具有统计学意义。
共纳入8087名青少年。我们共识别出99例ACLR，其中报告高MSP负荷的青少年中有6例（0.9%），报告低MSP负荷的青少年中有93例（1.3%）。与低MSP负荷的青少年相比，报告高MSP负荷的青少年发生ACLR的几率低23%（OR 0.77，95% CI 0.31至1.91）。然而，置信区间非常宽。
青少年自我报告的高MSP负荷与未来ACLR风险增加无关。尽管参与者数量众多，但ACLR病例相对较少，这意味着我们无法确定是否存在关联。
