Jurvelin J, Kiviranta I, Tammi M, Helminen J H
Clin Orthop Relat Res. 1986 Jun(207):246-52.
Using the indentation method, effects of immobilization with a splint for 11 weeks on the stiffness of the articular cartilage in the canine knee were investigated. Stiffness was determined for femoral, tibial, and patellar articular cartilages with nine, eight, and three test points, respectively, in the form of elastic moduli. Immobilization, without causing any macroscopic changes on cartilage surface, influenced the quality and quantity of articular cartilage. Immobilization caused significant softening of the femoral and tibial cartilages. The rate of deformation under the test load increased (42%) and the average thickness of the cartilage decreased (9%) as compared with the controls. Normal cartilage stiffness remained in the contact area between the patella and patellar surface of the femur, probably as a consequence of the sustained, but not forceful, loading between the femur and the patella produced by the flexion of the knee joint.
采用压痕法，研究了用夹板固定11周对犬膝关节软骨刚度的影响。分别在股骨、胫骨和髌骨关节软骨上选取9个、8个和3个测试点测定刚度，以弹性模量的形式表示。固定并未引起软骨表面的任何宏观变化，但影响了关节软骨的质量和数量。固定导致股骨和胫骨软骨显著软化。与对照组相比，试验载荷下的变形率增加了42%，软骨平均厚度减少了9%。髌股关节接触区域的软骨刚度保持正常，这可能是由于膝关节屈曲时股骨和髌骨之间持续但并非强力的加载所致。
