• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Always a bridesmaid, never a bride: Committing to flu neuraminidase as a vaccine target.总是伴娘，从未成新娘：致力于将流感神经氨酸酶作为疫苗靶点。
Mol Ther. 2023 Jul 5;31(7):1865-1867. doi: 10.1016/j.ymthe.2023.04.014. Epub 2023 May 17.
2
Infectious diseases. WHO ramps up bird flu vaccine efforts.传染病。世界卫生组织加大禽流感疫苗研发力度。
Science. 2004 Jan 30;303(5658):609. doi: 10.1126/science.303.5658.609.
3
A Novel Recombinant Influenza Virus Neuraminidase Vaccine Candidate Stabilized by a Measles Virus Phosphoprotein Tetramerization Domain Provides Robust Protection from Virus Challenge in the Mouse Model.一种新型重组流感病毒神经氨酸酶疫苗候选株，通过麻疹病毒磷酸蛋白四聚化结构域稳定，在小鼠模型中可提供针对病毒挑战的强大保护。
mBio. 2021 Dec 21;12(6):e0224121. doi: 10.1128/mBio.02241-21. Epub 2021 Nov 23.
4
Vaccination with Recombinant Parainfluenza Virus 5 Expressing Neuraminidase Protects against Homologous and Heterologous Influenza Virus Challenge.接种表达神经氨酸酶的重组副流感病毒5可抵御同源和异源流感病毒攻击。
J Virol. 2017 Nov 14;91(23). doi: 10.1128/JVI.01579-17. Print 2017 Dec 1.
5
Characterization of a neuraminidase-deficient influenza a virus as a potential gene delivery vector and a live vaccine.一种神经氨酸酶缺陷型甲型流感病毒作为潜在基因递送载体和活疫苗的特性研究
J Virol. 2004 Mar;78(6):3083-8. doi: 10.1128/jvi.78.6.3083-3088.2004.
6
A single cycle influenza virus coated in H7 haemagglutinin generates neutralizing antibody responses to haemagglutinin and neuraminidase glycoproteins and protection from heterotypic challenge.一种带有 H7 血凝素的单周期流感病毒能够产生针对血凝素和神经氨酸酶糖蛋白的中和抗体反应，并能提供针对异型挑战的保护。
J Gen Virol. 2019 Mar;100(3):431-445. doi: 10.1099/jgv.0.001228. Epub 2019 Feb 4.
7
Influenza Neuraminidase Characteristics and Potential as a Vaccine Target.流感神经氨酸酶的特性及其作为疫苗靶点的潜力。
Front Immunol. 2021 Nov 16;12:786617. doi: 10.3389/fimmu.2021.786617. eCollection 2021.
8
Influenza virus neuraminidase (NA): a target for antivirals and vaccines.流感病毒神经氨酸酶（NA）：抗病毒药物和疫苗的靶点。
Arch Virol. 2016 Aug;161(8):2087-94. doi: 10.1007/s00705-016-2907-7. Epub 2016 Jun 2.
9
Neuraminidase, the Forgotten Surface Antigen, Emerges as an Influenza Vaccine Target for Broadened Protection.神经氨酸酶，被遗忘的表面抗原，作为流感疫苗靶点出现，以实现更广泛的保护。
J Infect Dis. 2019 Apr 8;219(Suppl_1):S75-S80. doi: 10.1093/infdis/jiz017.
10
The antigenic landscape of human influenza N2 neuraminidases from 2009 until 2017.2009 年至 2017 年期间人类流感 N2 神经氨酸酶的抗原景观。
Elife. 2024 May 28;12:RP90782. doi: 10.7554/eLife.90782.

引用本文的文献

1
Isolation of human antibodies against influenza B neuraminidase and mechanisms of protection at the airway interface.乙型流感神经氨酸酶人源抗体的分离及其在气道界面的保护机制。
Immunity. 2024 Jun 11;57(6):1413-1427.e9. doi: 10.1016/j.immuni.2024.05.002. Epub 2024 May 31.

本文引用的文献

1
Neuraminidase delivered as an APC-targeted DNA vaccine induces protective antibodies against influenza.神经氨酸酶作为 APC 靶向 DNA 疫苗诱导针对流感的保护性抗体。
Mol Ther. 2023 Jul 5;31(7):2188-2205. doi: 10.1016/j.ymthe.2023.03.012. Epub 2023 Mar 16.
2
Antigen bivalency of antigen-presenting cell-targeted vaccines increases B cell responses.抗原呈递细胞靶向疫苗的抗原二价性增加了 B 细胞反应。
Cell Rep. 2022 May 31;39(9):110901. doi: 10.1016/j.celrep.2022.110901.
3
A single-shot adenoviral vaccine provides hemagglutinin stalk-mediated protection against heterosubtypic influenza challenge in mice.单剂量腺病毒疫苗为小鼠提供血凝素茎介导的针对异型流感病毒挑战的保护。
Mol Ther. 2022 May 4;30(5):2024-2047. doi: 10.1016/j.ymthe.2022.01.011. Epub 2022 Jan 7.
4
Adenoviral Vectors as Vaccines for Emerging Avian Influenza Viruses.腺病毒载体作为新兴禽流感病毒疫苗。
Front Immunol. 2021 Jan 29;11:607333. doi: 10.3389/fimmu.2020.607333. eCollection 2020.
5
Broadly protective human antibodies that target the active site of influenza virus neuraminidase.广谱保护性人源抗体靶向流感病毒神经氨酸酶的活性位点。
Science. 2019 Oct 25;366(6464):499-504. doi: 10.1126/science.aay0678.
6
Overcoming Barriers in the Path to a Universal Influenza Virus Vaccine.克服通用流感病毒疫苗道路上的障碍。
Cell Host Microbe. 2018 Jul 11;24(1):18-24. doi: 10.1016/j.chom.2018.06.016.
7
Influenza.流感。
Nat Rev Dis Primers. 2018 Jun 28;4(1):3. doi: 10.1038/s41572-018-0002-y.
8
NAction! How Can Neuraminidase-Based Immunity Contribute to Better Influenza Virus Vaccines?神经氨酸酶为基础的免疫作用如何能有助于更好的流感病毒疫苗？
mBio. 2018 Apr 3;9(2):e02332-17. doi: 10.1128/mBio.02332-17.
9
In the shadow of hemagglutinin: a growing interest in influenza viral neuraminidase and its role as a vaccine antigen.在血凝素的影响下：对流感病毒神经氨酸酶及其作为疫苗抗原的作用的兴趣与日俱增。
Viruses. 2014 Jun 23;6(6):2465-94. doi: 10.3390/v6062465.
10
Association of serum anti-neuraminidase antibody with resistance to influenza in man.血清抗神经氨酸酶抗体与人类对流感的抵抗力的关联。
N Engl J Med. 1972 Jun 22;286(25):1329-32. doi: 10.1056/NEJM197206222862502.

Always a bridesmaid, never a bride: Committing to flu neuraminidase as a vaccine target.

作者信息

Schneider Cosette, Coughlan Lynda

机构信息

Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201, USA; Graduate Program in Life Sciences (GPILS), Molecular Microbiology and Immunology Program, University of Maryland School of Medicine Baltimore, Baltimore, MD 21201, USA.

Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201, USA; Center for Vaccine Development and Global Health (CVD), University of Maryland School of Medicine, Baltimore, MD 21201, USA.

出版信息

Mol Ther. 2023 Jul 5;31(7):1865-1867. doi: 10.1016/j.ymthe.2023.04.014. Epub 2023 May 17.

DOI:10.1016/j.ymthe.2023.04.014
PMID:37201525
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10362412/
Abstract
摘要