CGBio Co. Ltd., Seoul, Republic of Korea; Department of Biomedical Engineering, Chungbuk National University, Cheongju, Republic of Korea.
CGBio Co. Ltd., Seoul, Republic of Korea.
World Neurosurg. 2023 Dec;180:e1-e10. doi: 10.1016/j.wneu.2023.05.034. Epub 2023 May 17.
The objective of this study is to evaluate the subsidence performance of a bioactive glass-ceramic (CaO-SiO-PO-BO) spacer in terms of its modulus of elasticity and contact area using mechanical tests and finite element analysis.
Three spacer three-dimensional models (Polyether ether ketone [PEEK]-C: PEEK spacer with a small contact area; PEEK-NF: PEEK spacer with a large contact area; and Bioactive glass [BGS]-NF: bioactive glass-ceramic spacer with a large contact area) are constructed and placed between bone blocks for compression analysis. The stress distribution, peak von Mises stress, and reaction force generated in the bone block are predicted by applying a compressive load. Subsidence tests are conducted for three spacer models in accordance with ASTM F2267. Three types of blocks measuring 8, 10, and 15 pounds per cubic foot are used to account for the various bone qualities of patients. A statistical analysis of the results is conducted using a one-way Analysis of variance and post hoc analysis (Tukey's Honestly Significant Difference) by measuring the stiffness and yield load.
The stress distribution, peak von Mises stress, and reaction force predicted via the finite element analysis are the highest for PEEK-C, whereas they are similar for PEEK-NF and BGS-NF. Results of mechanical tests show that the stiffness and yield load of PEEK-C are the lowest, whereas those of PEEK-NF and BGS-NF are similar.
The main factor affecting subsidence performance is the contact area. Therefore, bioactive glass-ceramic spacers exhibit a larger contact area and better subsidence performance than conventional spacers.
本研究旨在通过力学试验和有限元分析，评估生物活性玻璃陶瓷（CaO-SiO-PO-BO）间隔物的弹性模量和接触面积的沉降性能。
构建了三个间隔物三维模型（聚醚醚酮[PEEK]-C：具有小接触面积的 PEEK 间隔物；PEEK-NF：具有大接触面积的 PEEK 间隔物；和生物活性玻璃[BGS]-NF：具有大接触面积的生物活性玻璃陶瓷间隔物），并将其放置在骨块之间进行压缩分析。通过施加压缩载荷，预测骨块中的应力分布、峰值 von Mises 应力和反力。根据 ASTM F2267 对三个间隔物模型进行沉降试验。使用三种每立方英尺 8、10 和 15 磅的块来考虑患者不同的骨质量。通过测量刚度和屈服载荷，对结果进行单因素方差分析和事后分析（Tukey 的诚实显着差异）的统计分析。
通过有限元分析预测的应力分布、峰值 von Mises 应力和反力对于 PEEK-C 最高，而对于 PEEK-NF 和 BGS-NF 则相似。力学试验结果表明，PEEK-C 的刚度和屈服载荷最低，而 PEEK-NF 和 BGS-NF 的则相似。
影响沉降性能的主要因素是接触面积。因此，生物活性玻璃陶瓷间隔物比传统间隔物具有更大的接触面积和更好的沉降性能。
