Department of Endocrinology and Nutrition, Ciudad Real General University Hospital, Ciudad Real, Spain; Department of Endocrinology and Nutrition, Guadalajara University Hospital, Guadalajara, Spain.
Department of Endocrinology and Nutrition, Toledo University Hospital, Toledo, Spain.
Sci Total Environ. 2023 Sep 1;889:164045. doi: 10.1016/j.scitotenv.2023.164045. Epub 2023 May 17.
To evaluate the effect of the historic Spanish heatwave (9th-26th July 2022) over glycemic control in adults with type 1 diabetes (T1D).
Cross-sectional retrospective analysis of adult patients with T1D in Castilla-La Mancha (south-central Spanish region) using intermittently scanned continuous glucose monitoring (isCGM) during and after the heatwave. Primary outcome was change in time in range (TIR) 3.0-10 mmol/L (70-180 mg/dL) of interstitial glucose in the two weeks following the heatwave.
A total of 2701 T1D patients were analyzed. We detected a TIR reduction of 4.0 % (95 % CI -3.4, -4.6; P < 0.001) in the two weeks following the heatwave. Patients in the highest daily scan frequency quartile (>13 scans/day) during the heatwave showed the greatest deterioration in TIR after it concluded (-5.4 % [95 % CI -6.5, -4.3; P < 0.001]). The percentage of patients meeting all the recommendations of the International Consensus of Time in Range was greater during the heatwave than after it ended (10.6 % vs. 8.4 %, P < 0.001).
Adults with T1D had better glycemic control during the historic Spanish heatwave compared to the following period.
评估历史上的西班牙热浪（2022 年 7 月 9 日至 26 日）对 1 型糖尿病（T1D）成人患者血糖控制的影响。
使用间歇性扫描连续血糖监测（isCGM）对卡斯蒂利亚-拉曼恰（西班牙中南部地区）的成年 T1D 患者进行回顾性横断面分析，该分析在热浪期间和之后进行。主要结局是热浪后两周内 3.0-10mmol/L（70-180mg/dL）间质葡萄糖时间在目标范围内（TIR）的变化。
共分析了 2701 例 T1D 患者。我们发现热浪后两周 TIR 降低了 4.0%（95%CI-3.4，-4.6；P<0.001）。在热浪期间每日扫描频率最高的四分位组（>13 次/天）的患者，在热浪结束后 TIR 恶化最严重（-5.4%[95%CI-6.5，-4.3；P<0.001]）。在热浪期间，符合 TIR 所有建议的患者比例高于热浪结束后（10.6%比 8.4%，P<0.001）。
与热浪结束后的时期相比，患有 T1D 的成年人在历史上的西班牙热浪期间血糖控制更好。
