血小板活化因子作为食物过敏反应的内源性辅助因子。
Platelet-activating factor as an endogenous cofactor of food anaphylaxis.
作者信息
Pałgan Krzysztof, Tretyn Andrzej
机构信息
Department of Allergology, Clinical Immunology and Internal Diseases, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University, Bydgoszcz, Poland.
Faculty of Biological and Veterinary Sciences, Nicolaus Copernicus University, Toruń, Poland.
出版信息
Biofactors. 2023 Sep-Oct;49(5):976-983. doi: 10.1002/biof.1956. Epub 2023 May 19.
Anaphylaxis is a severe, acute, life-threatening generalized or systemic hypersensitivity reaction. The incidence of anaphylaxis is increasing worldwide, with medications and food contributing to most cases. Physical exercise, acute infections, drugs, alcohol, and menstruation are the external cofactors associated with more severe systemic reaction. The aim of this review is to show that platelet-activating factor contributes to the development of severe anaphylactic reaction, and even to anaphylactic shock.
过敏反应是一种严重、急性、危及生命的全身性或系统性超敏反应。全球范围内过敏反应的发病率正在上升，其中药物和食物导致了大多数病例。体育锻炼、急性感染、药物、酒精和月经是与更严重的全身反应相关的外部辅助因素。本综述的目的是表明血小板活化因子促成严重过敏反应的发生，甚至促成过敏性休克。
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