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在 COVID-19 大流行期间使用口罩与哮喘青少年患者呼吸困难有关。

Face mask use during the COVID-19 pandemic was associated with breathing difficulties in adolescent patients with asthma.

机构信息

Department of Paediatrics and Adolescent Medicine, Lillebaelt Hospital, University Hospital of Southern Denmark, Kolding, Denmark.

Department of Regional Health Research, University of Southern Denmark, Odense, Denmark.

出版信息

Acta Paediatr. 2023 Aug;112(8):1740-1746. doi: 10.1111/apa.16852. Epub 2023 Jun 1.

DOI:10.1111/apa.16852
PMID:37203993
Abstract

AIM

Face masks have been used to prevent severe acute respiratory syndrome coronavirus-2 transmission. We investigated the impact of face mask use on paediatric patients with asthma.

METHODS

Between February 2021 and January 2022, we surveyed adolescents aged 10-17 attending the paediatric outpatient clinic at the Lillebaelt Hospital, Kolding, Denmark with asthma, other breathing problems or no breathing problems.

RESULTS

We recruited 408 participants (53.4% girls) with a median age of 14 years: 312 in the asthma group, 37 in the other breathing problems group and 59 in the no breathing problems group. Most participants experienced mask-related breathing impairment. The relative risk (RR) of experiencing severe breathing problems, compared to no problems, was more than four times as high for adolescents with asthma (RR 4.6, 95% CI 1.3-16.8, p = 0.02) than adolescents with no breathing problems. More than a third (35.9%) of the asthma group experienced mild asthma and 3.9% had severe asthma. Girls experienced more mild (RR 1.9, 95% CI 1.2-3.1, p < 0.01) and severe (RR 6.6, 95% CI 3.1-13.8, p < 0.01) symptoms than boys. Age had no effect. Adequate asthma control minimised negative effects.

CONCLUSION

Face masks caused significant breathing impairment in most adolescents, particularly in those with asthma.

摘要

目的

口罩已被用于预防严重急性呼吸综合征冠状病毒 2 型的传播。我们研究了口罩使用对患有哮喘的儿科患者的影响。

方法

在 2021 年 2 月至 2022 年 1 月期间,我们调查了在丹麦科灵的 Lillebaelt 医院儿科门诊就诊的 10-17 岁青少年,他们患有哮喘、其他呼吸问题或无呼吸问题。

结果

我们招募了 408 名参与者(53.4%为女孩),中位年龄为 14 岁:312 名在哮喘组,37 名在其他呼吸问题组,59 名在无呼吸问题组。大多数参与者经历了与口罩相关的呼吸障碍。与无问题相比,哮喘青少年(RR 4.6,95%CI 1.3-16.8,p=0.02)出现严重呼吸问题的相对风险(RR)高出四倍以上,而无呼吸问题的青少年则高出四倍以上。哮喘组中超过三分之一(35.9%)的青少年患有轻度哮喘,3.9%的青少年患有重度哮喘。女孩经历了更多的轻度(RR 1.9,95%CI 1.2-3.1,p<0.01)和重度(RR 6.6,95%CI 3.1-13.8,p<0.01)症状比男孩多。年龄没有影响。适当的哮喘控制可最大程度地减少负面影响。

结论

口罩会导致大多数青少年出现明显的呼吸障碍,尤其是患有哮喘的青少年。

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