Department of Veterinary Pathology, College of Veterinary Medicine, Kyungpook National University, Daegu, Republic of Korea.
J Vet Diagn Invest. 2023 Jul;35(4):390-394. doi: 10.1177/10406387231174233. Epub 2023 May 19.
An unknown-aged adult female wild boar () was brought to Kyungpook National University for postmortem examination. Gross examination revealed gallbladder agenesis. Histologically, the liver was cirrhotic and had intrahepatic cholelithiasis, the choleliths were yellow, brown, gray, and black, and had coffin-lid and pyramidal appearances. Fourier-transform infrared spectroscopy analysis revealed that the components were 80% struvite and 20% calcium oxalate monohydrate. Chronic inflammatory cell infiltration was observed, with hyperplastic hepatocellular nodules characterized by large nuclei, prominent nucleoli, and scant cytoplasm with frequent binucleation, surrounded by thick fibrous septa. The epithelium of intrahepatic bile ducts that contained choleliths had undergone gallbladder-like metaplasia, which might have been induced by chronic irritation from the stones or by the accompanying chronic bacterial infection that was observed in Gram stains.
一头未知年龄的成年雌性野猪（）被带到庆北国立大学进行剖检。大体检查显示胆囊发育不全。组织学检查显示肝脏为肝硬化，并伴有肝内胆管结石，结石呈黄色、棕色、灰色和黑色，呈棺材盖和金字塔形外观。傅里叶变换红外光谱分析显示，成分 80%为鸟粪石，20%为一水合草酸钙。观察到慢性炎症细胞浸润，伴有大核、明显核仁、细胞质稀少、常双核的增生性肝细胞结节，周围有厚纤维性间隔。含有胆管结石的肝内胆管上皮发生了类似胆囊的化生，这可能是由结石的慢性刺激或革兰氏染色中观察到的伴随的慢性细菌感染引起的。
