Alatawi Saleha K
Faculty of Applied Medical Science, Al Baha University, KSA.
J Taibah Univ Med Sci. 2023 Mar 31;18(5):1157-1169. doi: 10.1016/j.jtumed.2023.03.008. eCollection 2023 Oct.
This study sought to translate the Keratoconus Outcomes Research Questionnaire (KORQ) and using it to measure and evaluate the quality of life of a sample of people with keratoconus in KSA.
A cross-sectional online survey of patients with keratoconus, drawn by convenience sampling from across several regions of KSA, was conducted. The data were analysed with appropriate quantitative techniques.
Ninety-one patients with keratoconus (57.1% men; mean age = 33.25 ± 6.72 years) from five regions of KSA completed the survey. A total of 78.1% of the cases were diagnosed when the respondents were 15-29 years of age. Of the 91 participants, 11%, 27%, and 30% reported no, mild, and moderate interference with activities, whereas 17% and 15% reported substantial activity limitations. Regarding symptoms, 8%, 20%, and 24% reported no, mild, and moderate symptoms, whereas 23% and 25% reported substantial and extreme symptoms, respectively. Pearson rank correlation analysis indicated strong and statistically significant coefficients among the coded scores for symptoms, activity limitations and demographic factors. Regression analysis of the relationship between the scores for symptoms/activity limitations and demographic factors indicated that only the scores for visual acuity, eye with keratoconus, and geographic region were statistically significant at 5%. Visual acuity while wearing glasses or lenses and the odds of having poor QoL score were higher in both the left and right eyes [23.85 (95% CI, 4.21 to 135.24) and 6.0 (95% CI, 1.12 to 32.12), respectively]. Unknown visual acuity is associated with greater odds of higher annoyance scores [4.69 (95% CI, 1.06 to 20.62) and 13.63 (95% CI, 2.74 to 67.74), respectively].
Patients experience substantial impairments in their daily lives that could potentially be mitigated by addressing visual acuity, specific (left, right or both) eyes with keratoconus, and regional variables.
本研究旨在翻译圆锥角膜结局研究问卷（KORQ），并使用该问卷测量和评估沙特阿拉伯圆锥角膜患者样本的生活质量。
通过便利抽样，对来自沙特阿拉伯多个地区的圆锥角膜患者进行了横断面在线调查。采用适当的定量技术对数据进行分析。
来自沙特阿拉伯五个地区的91名圆锥角膜患者（57.1%为男性；平均年龄 = 33.25 ± 6.72岁）完成了调查。共有78.1%的病例在受访者15 - 29岁时被诊断出来。在91名参与者中，11%、27%和30%报告活动未受干扰、轻度干扰和中度干扰，而17%和15%报告活动受到严重限制。关于症状，8%、20%和24%报告无症状、轻度症状和中度症状，而23%和25%分别报告有严重症状和极端症状。Pearson等级相关分析表明，症状、活动限制和人口统计学因素的编码分数之间存在强且具有统计学意义的系数。症状/活动限制分数与人口统计学因素之间关系的回归分析表明，只有视力分数、患圆锥角膜的眼睛以及地理区域在5%水平上具有统计学意义。佩戴眼镜或隐形眼镜时的视力以及生活质量得分较低的几率在左眼和右眼均较高[分别为23.85（95%置信区间，4.21至135.24）和6.0（95%置信区间，1.12至32.12）]。未知视力与更高烦恼分数几率的增加相关[分别为4.69（95%置信区间，1.06至20.62）和13.63（95%置信区间，2.74至67.74）]。
患者在日常生活中经历了严重损害，通过解决视力、特定（左眼、右眼或双眼）患圆锥角膜的眼睛以及区域变量，这些损害可能会得到缓解。
