[大鼠3-甲基胆蒽诱导白血病中病毒特异性功能的表达]
[Expression of virus-specific functions in 3-methylcholanthrene-induced leukemia in rats].
作者信息
Keszeghová V, Veselovská Z, Hlavayová E, Svec J
出版信息
Eksp Onkol. 1986;8(3):21-8.
PMID:3720637
Abstract
It was isolated and identified MR-Le virus from Wistar rats with myelogenous leukemia. The comparison of isolated in vivo and in vitro MR-Le virus with endogenous oncovirus RaLV in protein profile as well as results of molecular hybridization pointed out that RaLV did not participate in the induction of MR leukemia. The question about the role of MR-Le virus in the etiology of MR leukemia is opened now.
摘要
从患有髓性白血病的Wistar大鼠中分离并鉴定出MR-Le病毒。对体内和体外分离的MR-Le病毒与内源性肿瘤病毒RaLV的蛋白质谱进行比较以及分子杂交结果表明，RaLV不参与MR白血病的诱导。目前，关于MR-Le病毒在MR白血病病因学中的作用问题仍未解决。
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