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一例亚急性支架血栓形成病例。

A Case of Subacute Stent Thrombosis.

作者信息

Mijares-Rojas Ivan A, Martinez Enrique F, Leonor Lopez George L, De Marchena Eduardo, Alfonso Carlos E

机构信息

Internal Medicine, University of Miami Miller School of Medicine, Jackson Memorial Hospital, Miami, USA.

Internal Medicine, John H. Stroger, Jr. Hospital of Cook County, Chicago, USA.

出版信息

Cureus. 2023 Apr 17;15(4):e37725. doi: 10.7759/cureus.37725. eCollection 2023 Apr.

DOI:10.7759/cureus.37725
PMID:37206507
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10191453/
Abstract

A 67-year-old male presenting with an anterior ST-segment elevation myocardial infarction (STEMI) underwent stent placement in the left anterior descending coronary. The patient was discharged on an appropriate medical regimen containing dual antiplatelet therapy (DAPT). Four days later, the patient presented with repeat acute coronary syndrome symptomatology. Electrocardiogram demonstrated ongoing STEMI in the previously treated artery distribution. Emergency angiography revealed restenosis and total thrombotic occlusion. Post-intervention stenosis was 0% after aspiration thrombectomy and balloon angioplasty. Stent thrombosis is a high-mortality and therapeutically challenging condition requiring prepared clinicians who recognize predisposing risk factors and initiate early management.

摘要

一名67岁男性因前壁ST段抬高型心肌梗死(STEMI)接受了左前降支冠状动脉支架置入术。患者出院时接受了包含双重抗血小板治疗(DAPT)的适当药物治疗方案。四天后,患者再次出现急性冠状动脉综合征症状。心电图显示在先前治疗的动脉分布区域存在持续性STEMI。急诊血管造影显示再狭窄和完全血栓性闭塞。抽吸血栓切除术和球囊血管成形术后干预后狭窄率为0%。支架血栓形成是一种高死亡率且治疗具有挑战性的疾病,需要有经验的临床医生识别易患风险因素并尽早进行管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f242/10191453/8847f78ae8a2/cureus-0015-00000037725-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f242/10191453/02e0c307de83/cureus-0015-00000037725-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f242/10191453/1fd5c13483f1/cureus-0015-00000037725-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f242/10191453/dd1b93e691f8/cureus-0015-00000037725-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f242/10191453/0fb21728972a/cureus-0015-00000037725-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f242/10191453/8847f78ae8a2/cureus-0015-00000037725-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f242/10191453/02e0c307de83/cureus-0015-00000037725-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f242/10191453/1fd5c13483f1/cureus-0015-00000037725-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f242/10191453/dd1b93e691f8/cureus-0015-00000037725-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f242/10191453/0fb21728972a/cureus-0015-00000037725-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f242/10191453/8847f78ae8a2/cureus-0015-00000037725-i05.jpg

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本文引用的文献

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Incidence, Predictors, and Outcomes of Acute and Sub-acute Stent Thrombosis after Emergency Percutaneous Coronary Revascularization with Drug-Eluting Stents: A Prospective Observational Study.急性和亚急性支架血栓形成后急诊经皮冠状动脉血运重建与药物洗脱支架的发生率、预测因素和结局:一项前瞻性观察研究。
Glob Heart. 2022 Mar 30;17(1):24. doi: 10.5334/gh.1112. eCollection 2022.
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Drug-eluting stent thrombosis: current and future perspectives.药物洗脱支架血栓形成:当前和未来的观点。
Cardiovasc Interv Ther. 2021 Apr;36(2):158-168. doi: 10.1007/s12928-021-00754-x. Epub 2021 Jan 13.
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Outcomes After First- Versus Second-Generation Drug-Eluting Stent Thrombosis (from the REAL-ST Registry).
第一代与第二代药物洗脱支架血栓形成后的结局(来自 REAL-ST 注册研究)。
Am J Cardiol. 2020 Oct 1;132:52-58. doi: 10.1016/j.amjcard.2020.07.011. Epub 2020 Jul 14.
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Identification of Patient-Related Factors in Stent Thrombosis.支架内血栓形成中患者相关因素的识别。
Circ J. 2020 Aug 25;84(9):1464-1466. doi: 10.1253/circj.CJ-20-0674. Epub 2020 Jul 31.
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Contemporary management of stent thrombosis: Predictors of mortality and the role of new-generation drug-eluting stents.当代支架血栓的处理:死亡率的预测因素和新一代药物洗脱支架的作用。
Catheter Cardiovasc Interv. 2020 Jul;96(1):E8-E16. doi: 10.1002/ccd.28467. Epub 2019 Sep 9.
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Predictors of stent thrombosis and their implications for clinical practice.支架血栓形成的预测因素及其对临床实践的影响。
Nat Rev Cardiol. 2019 Apr;16(4):243-256. doi: 10.1038/s41569-018-0118-5.
7
Acute Coronary Stent Thrombosis in Modern Era: Etiology, Treatment, and Prognosis.现代急性冠状动脉支架血栓形成:病因、治疗及预后
Cardiology. 2017;137(4):246-255. doi: 10.1159/000464404. Epub 2017 May 5.
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Stent thrombosis: a clinical perspective.支架血栓形成:临床观点。
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Risk of stent thrombosis among bare-metal stents, first-generation drug-eluting stents, and second-generation drug-eluting stents: results from a registry of 18,334 patients.裸金属支架、第一代药物洗脱支架和第二代药物洗脱支架的支架血栓形成风险:来自 18334 名患者的注册研究结果。
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