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Case Report: ST-Elevation Myocardial Infarction Secondary to Acute Atherothrombotic Occlusion Treated With No Stent Strategy.

作者信息

Dhawan Rahul, Samant Saurabhi, Gajanan Ganesh, Chatzizisis Yiannis S

机构信息

Cardiovascular Division, Mayo Clinic, Rochester, MN, United States.

Cardiovascular Division, University of Nebraska Medical Center, Omaha, NE, United States.

出版信息

Front Cardiovasc Med. 2022 Feb 25;9:834676. doi: 10.3389/fcvm.2022.834676. eCollection 2022.

DOI:10.3389/fcvm.2022.834676
PMID:35282355
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8916537/
Abstract

BACKGROUND

Intravascular imaging plays a vital role in the pathophysiology-based diagnosis and treatment of patients with ST-elevation myocardial infarction (STEMI). We present a case of STEMI due to plaque erosion, which was managed with a no stent approach.

CASE SUMMARY

A 43-year-old female with a history of tobacco abuse presented with an anterior STEMI. Coronary angiography revealed acute thrombotic occlusion of the left anterior descending artery with spontaneous recanalization. Intravascular imaging with optical coherence tomography (OCT) demonstrated plaque erosion as the underlying etiology for the acute thrombotic occlusion. A no stent strategy with aspiration thrombectomy and dual antiplatelet therapy was used to manage the patient given that there was no evidence of plaque rupture. Repeat coronary imaging was done at 2 months to assess the status of the lesion.

CONCLUSION

A 43-year-old female with STEMI due to plaque erosion was successfully managed only by thrombus aspiration and not by angioplasty and stent placement. Individualized treatment approaches in patients with acute coronary syndromes, can not only achieve optimal management goals but also avoid unnecessary complications associated with interventions. This case illustrates how intracoronary imaging and pathophysiology-guided treatment can dramatically change management. In this young patient, STEMI was managed purely by thrombus aspiration. Intravascular imaging obviated the need for stent placement possibly preventing stent-related complications including restenosis and thrombosis.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/735a/8916537/c1a79118696d/fcvm-09-834676-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/735a/8916537/6e07e019630a/fcvm-09-834676-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/735a/8916537/c1a79118696d/fcvm-09-834676-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/735a/8916537/6e07e019630a/fcvm-09-834676-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/735a/8916537/c1a79118696d/fcvm-09-834676-g0002.jpg

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本文引用的文献

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Coronary Computer Tomography Angiography in 2021-Acquisition Protocols, Tips and Tricks and Heading beyond the Possible.2021年冠状动脉计算机断层扫描血管造影——采集方案、技巧及超越可能的进展
Diagnostics (Basel). 2021 Jun 10;11(6):1072. doi: 10.3390/diagnostics11061072.
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Role of Cardiac Magnetic Resonance to Improve Risk Prediction Following Acute ST-Elevation Myocardial Infarction.心脏磁共振成像在改善急性ST段抬高型心肌梗死风险预测中的作用
J Clin Med. 2020 Apr 7;9(4):1041. doi: 10.3390/jcm9041041.
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Clinical and Laboratory Predictors for Plaque Erosion in Patients With Acute Coronary Syndromes.
急性冠状动脉综合征患者斑块侵蚀的临床和实验室预测因子。
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In vivo predictors of plaque erosion in patients with ST-segment elevation myocardial infarction: a clinical, angiographical, and intravascular optical coherence tomography study.在 ST 段抬高型心肌梗死患者中易损斑块的体内预测因子:一项临床、血管造影和血管内光学相干断层成像研究。
Eur Heart J. 2018 Jun 7;39(22):2077-2085. doi: 10.1093/eurheartj/ehy101.
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EROSION Study (Effective Anti-Thrombotic Therapy Without Stenting: Intravascular Optical Coherence Tomography-Based Management in Plaque Erosion): A 1-Year Follow-Up Report.EROSION 研究(不支架植入的有效抗血栓治疗:基于血管内光学相干断层成像的斑块侵蚀管理):1 年随访报告。
Circ Cardiovasc Interv. 2017 Dec;10(12). doi: 10.1161/CIRCINTERVENTIONS.117.005860.
6
Acute Coronary Syndromes: The Way Forward From Mechanisms to Precision Treatment.急性冠状动脉综合征:从发病机制到精准治疗的未来之路
Circulation. 2017 Sep 19;136(12):1155-1166. doi: 10.1161/CIRCULATIONAHA.117.029870.
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