不同成因泪道阻塞时泪器的形态学特征
Morphological Characteristics of the Lacrimal Apparatus in its Obstruction of Various Genesis.
作者信息
Demyashkin Grigory A, Yartsev Vasily D, Atkova Eugenia L, Ekaterinchev Maxim A, Shchekin Vladimir I
机构信息
I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.
A.F. Tsyb Medical Radiological Research Center - a branch of the "National Medical Research Center of Radiology", Moscow, Russia.
出版信息
Indian J Otolaryngol Head Neck Surg. 2023 Apr;75(Suppl 1):951-956. doi: 10.1007/s12070-023-03493-y. Epub 2023 Feb 4.
Secondary acquired lacrimal duct obstruction (SALDO) is one of the complications of radioiodine therapy. The material was obtained during endoscopic dacryocystorhinostomy with revision of Hasner's valve in patients with PANDO (n = 7) in the distal segments of the nasolacrimal duct and in patients with SALDO (n = 7) after radioactive iodine therapy. The material was stained with hemotoxylin and eosin, alcyan blue, and by Masson method. Morphological and morphometric analyses were performed in semi-automatic mode. The results of histochemical staining of sections were translated into points taking into account the area and optical density (chromogenicity). The differences were considered significant at p < 0.05. It was shown that the nasolacrimal duct sclerosis is significantly lower (p = 0.029) in patients with SALDO than in patients with PANDO while fibrosis in the lacrimal sac is the same in patients of the compared groups.
继发性获得性泪道阻塞（SALDO）是放射性碘治疗的并发症之一。材料取自患有原发性获得性泪道阻塞（PANDO，n = 7）患者鼻泪管远端段行内镜下泪囊鼻腔造口术并修复哈氏瓣时，以及放射性碘治疗后患有SALDO（n = 7）的患者。材料用苏木精和伊红、阿尔辛蓝以及采用Masson方法染色。形态学和形态计量学分析以半自动模式进行。切片的组织化学染色结果根据面积和光密度（显色性）转化为分数。差异在p < 0.05时被认为具有显著性。结果显示，SALDO患者鼻泪管硬化程度显著低于PANDO患者（p = 0.029），而泪囊纤维化在比较组患者中相同。
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