Department of Clinical and Molecular Medicine, Sapienza University, Via di Grottarossa n. 1035, Rome, 00189, Italy.
Division of University Cardiology, IRCCS Galeazzi-Sant'Ambrogio Hospital, University of Milan, Milan, Italy.
Eur Heart J. 2023 Nov 1;44(41):4340-4356. doi: 10.1093/eurheartj/ehad342.
Since the publication of the 2015 EAPCI consensus on rotational atherectomy, the number of percutaneous coronary interventions (PCI) performed in patients with severely calcified coronary artery disease has grown substantially. This has been prompted on one side by the clinical demand for the continuous increase in life expectancy, the sustained expansion of the primary PCI networks worldwide, and the routine performance of revascularization procedures in elderly patients; on the other side, the availability of new and dedicated technologies such as orbital atherectomy and intravascular lithotripsy, as well as the optimization of the rotational atherectomy system, has increased operators' confidence in attempting more challenging PCI. This current EAPCI clinical consensus statement prepared in collaboration with the EURO4C-PCR group describes the comprehensive management of patients with heavily calcified coronary stenoses, starting with how to use non-invasive and invasive imaging to assess calcium burden and inform procedural planning. Objective and practical guidance is provided on the selection of the optimal interventional tool and technique based on the specific calcium morphology and anatomic location. Finally, the specific clinical implications of treating these patients are considered, including the prevention and management of complications and the importance of adequate training and education.
自 2015 年 EAPCI 关于旋磨术的共识发布以来,在严重钙化性冠状动脉疾病患者中进行经皮冠状动脉介入治疗(PCI)的数量大幅增加。这一方面是由于临床对预期寿命持续增长的需求,全球初级 PCI 网络的持续扩张,以及老年患者常规进行血运重建手术;另一方面,由于新型专用技术(如轨道旋磨术和血管内碎石术)的应用,以及旋磨术系统的优化,增加了术者对更具挑战性 PCI 的信心。这份由 EAPCI 与 EURO4C-PCR 合作编写的临床共识声明描述了严重钙化性冠状动脉狭窄患者的综合管理,首先是如何使用非侵入性和侵入性影像学检查来评估钙负荷并为手术规划提供信息。根据特定的钙形态和解剖位置,提供了关于选择最佳介入工具和技术的客观实用指南。最后,还考虑了治疗这些患者的具体临床意义,包括并发症的预防和处理,以及充分的培训和教育的重要性。