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头足类光感受器中光激活的视黄酸转运

Light-activated retinoid transport in cephalopod photoreceptors.

作者信息

Breneman J W, Robles L J, Bok D

出版信息

Exp Eye Res. 1986 Jun;42(6):645-58. doi: 10.1016/0014-4835(86)90053-9.

DOI:10.1016/0014-4835(86)90053-9
PMID:3720876
Abstract

Retinoid transport and chromophore exchange have been investigated in cephalopods using autoradiographic and radiobiochemical techniques. In dark adapted retinas, [3H]-retinoid is concentrated in myeloid bodies present in the photoreceptor inner segments and is bound to the photopigment retinochrome. In retinas exposed to light, there is a shift in the distribution of [3H]-retinoid. The rhabdomes become more heavily labeled than the inner segments, and rhodopsin labeling exceeds that of retinochrome. In animals returned to the dark, another shift in retinoid distribution occurs and the inner segments are again more labeled than the rhabdomes. In these animals [3H]-retinoid is bound primarily to retinochrome. Exposure to light seems to activate a transport mechanism that results in the redistribution of retinoid between the inner segments and rhabdomes and chromophore exchange among the photopigments.

摘要

利用放射自显影和放射生物化学技术,对头足类动物的类视黄醇转运和发色团交换进行了研究。在暗适应的视网膜中,[3H] - 类视黄醇集中在光感受器内段的髓样小体中,并与光色素视紫红质结合。在暴露于光的视网膜中,[3H] - 类视黄醇的分布发生了变化。视杆变得比内段标记更重,视紫红质的标记超过了视紫红质。在回到黑暗中的动物中,类视黄醇分布再次发生变化,内段再次比视杆标记更多。在这些动物中,[3H] - 类视黄醇主要与视紫红质结合。暴露于光似乎激活了一种转运机制,导致类视黄醇在内段和视杆之间重新分布,以及光色素之间的发色团交换。

相似文献

1
Light-activated retinoid transport in cephalopod photoreceptors.头足类光感受器中光激活的视黄酸转运
Exp Eye Res. 1986 Jun;42(6):645-58. doi: 10.1016/0014-4835(86)90053-9.
2
Retinoid cycling proteins redistribute in light-/dark-adapted octopus retinas.视黄醛循环蛋白在明暗适应的章鱼视网膜中重新分布。
J Comp Neurol. 1995 Aug 7;358(4):605-14. doi: 10.1002/cne.903580412.
3
Autoradiographic and biochemical analysis of photoreceptor membrane renewal in Octopus retina.
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4
Immunocytochemical localization of retinal binding protein in the octopus retina: a shuttle protein for 11-cis retinal.视网膜结合蛋白在章鱼视网膜中的免疫细胞化学定位:一种用于11-顺式视黄醛的穿梭蛋白。
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Immunocytochemical localization of photopigments in cephalopod retinae.头足类视网膜中光色素的免疫细胞化学定位。
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6
Retinal-binding protein as a shuttle for retinal in the rhodopsin-retinochrome system of the squid visual cells.视网膜结合蛋白作为视网膜在鱿鱼视觉细胞视紫红质-视黄醛色素系统中传递视网膜的载体。
Vision Res. 1989;29(6):639-52. doi: 10.1016/0042-6989(89)90026-6.
7
Distribution of rhodopsin and retinochrome in the squid retina.视紫红质和视黄醛色素在鱿鱼视网膜中的分布。
J Gen Physiol. 1976 Jun;67(6):791-805. doi: 10.1085/jgp.67.6.791.
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Addition of the chromophore to rat rhodopsin is an early post-translational event.
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Bright environmental light accelerates rhodopsin depletion in retinoid-deprived rats.明亮的环境光会加速类视黄醇缺乏大鼠视紫红质的消耗。
Invest Ophthalmol Vis Sci. 1993 May;34(6):2000-8.
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Histochemical localization of retinochrome and rhodopsin studied by fluorescence microscopy.通过荧光显微镜研究视黄醛色素和视紫红质的组织化学定位。
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