2,2'-联吡啶-6-碳硫酰胺衍生物作为潜在的抗肿瘤药物。
2,2'-Bipyridyl-6-carbothioamide derivatives as potential antitumor agents.
作者信息
Antonini I, Cristalli G, Franchetti P, Grifantini M, Martelli S, Filippeschi S
出版信息
Farmaco Sci. 1986 May;41(5):346-54. doi: 10.1002/chin.198646232.
PMID:3720944
Abstract
4- and/or 4'-substituted 2,2'-bipyridyl-6-carbothioamides have been synthesized and tested for their activity against P-388 lymphocytic leukemia in mice. Of these, only 4'-nitro-2,2'-bipyridyl-6-carbotioamide (IV c) proved to be active.
摘要
已合成了4-和/或4'-取代的2,2'-联吡啶-6-碳硫酰胺，并对其抗小鼠P-388淋巴细胞白血病的活性进行了测试。其中，只有4'-硝基-2,2'-联吡啶-6-碳硫酰胺（IV c）被证明具有活性。
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