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Trimethoprim/Sulfamethoxazole 耐药卡氏游动放线菌感染的表现与治疗。

Manifestations and Management of Trimethoprim/Sulfamethoxazole-Resistant Nocardia otitidiscaviarum Infection.

出版信息

Emerg Infect Dis. 2023 Jun;29(6):1266-1267. doi: 10.3201/eid2906.221854.

DOI:10.3201/eid2906.221854
PMID:37209690
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10202867/
Abstract

Nocardia can cause systemic infections with varying manifestations. Resistance patterns vary by species. We describe N. otitidiscavarium infection with pulmonary and cutaneous manifestations in a man in the United States. He received multidrug treatment that included trimethoprim/sulfamethoxazole but died. Our case highlights the need to treat with combination therapy until drug susceptibilities are known.

摘要

奴卡菌可引起表现各异的全身感染。耐药模式因菌种而异。我们在美国报告了一例表现为肺部和皮肤受累的耳炎奴卡菌感染病例,该患者接受了包括复方磺胺甲噁唑在内的多药治疗,但最终死亡。本病例强调了在药敏结果明确之前,需要采用联合治疗方案进行治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a00/10202867/a3aa998ae6ee/22-1854-F.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a00/10202867/a3aa998ae6ee/22-1854-F.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a00/10202867/a3aa998ae6ee/22-1854-F.jpg

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Epidemiology and Antimicrobial Resistance Profiles of the Species in China, 2009 to 2021.2009 年至 2021 年中国 种的流行病学和抗菌药物耐药谱。
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Clinical and laboratory features of the Nocardia spp. based on current molecular taxonomy.基于当前分子分类学的诺卡氏菌属的临床和实验室特征。
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In vitro activities of linezolid against multiple Nocardia species.利奈唑胺对多种诺卡菌属细菌的体外活性。
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