Dikensoy O, Filiz A, Bayram N, Balci I, Zer Y, Celik G, Ekinci E
Department of Pulmonary Disease, School of Medicine, Gaziantep University, Gaziantep, Turkey.
Int J Clin Pract. 2004 Feb;58(2):210-3. doi: 10.1111/j.1368-5031.2004.0133.x.
Nocardiosis is a rare disease, and worldwide, respiratory and disseminated infections are most often due to Nocardia asteroides which is recognised increasingly as an opportunistic infection in patients with underlying chronic debilitating disease or immunodeficiency. However, infection with N. otitidiscaviarum and pulmonary nocardiosis in an immune-competent host remains very rare. We report a 65-year-old immune-competent male with pulmonary N. otitidiscaviarum infection in whom complete cure was provided with a 6 months of antibiotic combination including trimethoprim-sulfomethaxazol. This is the first report of pulmonary N. otitidiscaviarum infection in an immune-competent patient from Turkey.
诺卡菌病是一种罕见疾病,在全球范围内,呼吸道感染和播散性感染最常由星形诺卡菌引起,该菌越来越被认为是患有潜在慢性衰弱性疾病或免疫缺陷患者的机会性感染病原体。然而,免疫功能正常宿主感染耳腔诺卡菌及发生肺诺卡菌病的情况仍然非常罕见。我们报告了一名65岁免疫功能正常的男性,其感染了耳腔诺卡菌,通过使用包括甲氧苄啶-磺胺甲恶唑在内的抗生素联合治疗6个月后实现了完全治愈。这是来自土耳其的关于免疫功能正常患者发生耳腔诺卡菌肺部感染的首例报告。