盐酸丁咯地尔在下肢闭塞性动脉疾病IV期的疗效
Effects of buflomedil hydrochloride in occlusive arterial disease of the lower limbs stage IV.
作者信息
Briguglio F, Briguglio E, Di Marco V, Swat M, Materia G, Intilisano A
出版信息
J Int Med Res. 1986;14(3):115-23. doi: 10.1177/030006058601400301.
PMID:3721052
Abstract
Ten patients affected by occlusive arterial disease and presenting with skin lesions of the limbs were treated with buflomedil first i.v. and then orally, at a dosage of 600 mg/day. After a treatment period of 30 to 60 days, eight patients showed lesion regression with complete recovery; the remaining two patients dropped out of the study. The mechanism of action of buflomedil in healing skin lesions is also discussed.
摘要
十名患有闭塞性动脉疾病并伴有肢体皮肤病变的患者首先接受了静脉注射丁咯地尔治疗，然后口服，剂量为每日600毫克。经过30至60天的治疗期后，八名患者的病变出现消退并完全康复；其余两名患者退出了研究。文中还讨论了丁咯地尔治疗皮肤病变的作用机制。
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Effects of buflomedil hydrochloride in occlusive arterial disease of the lower limbs stage IV.盐酸丁咯地尔在下肢闭塞性动脉疾病IV期的疗效
J Int Med Res. 1986;14(3):115-23. doi: 10.1177/030006058601400301.
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Experience with buflomedil in peripheral arterial occlusive disease.丁咯地尔治疗周围动脉闭塞性疾病的经验
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A placebo-controlled study of the effects of intravenous Buflomedil on foot skin microcirculation in patients with severe intermittent claudication.一项关于静脉注射丁咯地尔对重度间歇性跛行患者足部皮肤微循环影响的安慰剂对照研究。
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[Vascular and hemorheologic effects of buflomedil chlorhydrate in chronic obliterative arteriopathies of the legs].盐酸丁咯地尔对下肢慢性闭塞性动脉病的血管及血液流变学影响
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引用本文的文献
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Buflomedil. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in peripheral and cerebral vascular diseases.丁咯地尔。对其药效学和药代动力学特性以及在周围血管疾病和脑血管疾病中的治疗效果的综述。
Drugs. 1987 May;33(5):430-60. doi: 10.2165/00003495-198733050-00002.
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