Tazi-Lakhsassi L, Abid A, Sehlane M
J Int Med Res. 1986;14(3):158-61. doi: 10.1177/030006058601400308.
Forty children all aged over 2 years and eutrophic were treated with the combination amoxycillin and clavulanic acid for various infections (twenty-three with meningitis, eleven with bronchial pneumonia, three with typhoid fever, two with lower urinary tract infections and one with ear infection of moderate severity). Nine of these patients had sickness during treatment which was mild and transient in the majority of cases and caused treatment to be stopped in only one case (2.5%). This low level of gastric tolerance should not concern the paediatrician faced with an infection due to (or most likely to be) a beta-lactamase producing micro-organism.
40名年龄均超过2岁且营养状况良好的儿童因各种感染接受阿莫西林与克拉维酸联合治疗(23例患脑膜炎,11例患支气管肺炎,3例患伤寒,2例患下尿路感染,1例患中度严重耳部感染)。这些患者中有9例在治疗期间出现不适,多数情况下症状轻微且短暂,仅1例(2.5%)因此停止治疗。面对由产β-内酰胺酶微生物引起(或极有可能由其引起)的感染时,这种较低的胃部耐受性不应引起儿科医生的担忧。