阿莫西林与克拉维酸联合用药对尿路感染的疗效
Activities of amoxicillin and clavulanic acid combinations against urinary tract infections.
作者信息
Crokaert F, van der Linden M P, Yourassowsky E
出版信息
Antimicrob Agents Chemother. 1982 Aug;22(2):346-9. doi: 10.1128/AAC.22.2.346.
Abstract
Urinary tract infection caused by beta-lactamase-producing bacteria were treated with 500 mg of amoxicillin three times daily plus either 250 or 125 mg of clavulanic acid three times daily. The overall cure rate was 63.6%, 77.7% with the high dose of clavulanic acid and 53.8% with the low dose. Gastrointestinal intolerance was common in the high-dose clavulanic acid regimen.
摘要
由产β-内酰胺酶细菌引起的尿路感染，采用每日三次、每次500毫克阿莫西林加每日三次、每次250毫克或125毫克克拉维酸进行治疗。总体治愈率为63.6%，高剂量克拉维酸组为77.7%，低剂量组为53.8%。高剂量克拉维酸治疗方案中胃肠道不耐受情况较为常见。
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本文引用的文献
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2
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3
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4
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J Appl Bacteriol. 1980 Aug;49(1):111-8. doi: 10.1111/j.1365-2672.1980.tb01048.x.
5
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6
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