Robinson G C, Conry R F
Dev Med Child Neurol. 1986 Jun;28(3):294-8. doi: 10.1111/j.1469-8749.1986.tb03875.x.
The maternal age of two groups of children with congenital handicaps, cerebral palsy and fetal alcohol syndrome (FAS), were examined and compared with a group of mothers of children with congenital optic-nerve hypoplasia (CONH). The maternal age of children with CONH was significantly less than for the cerebral-palsied children which, in turn, was significantly less than for the FAS children. In addition, about one-half of the children with CONH had associated handicaps which clustered into four progressively more severe combinations. Maternal age and the occurrence of endocrine problems did not differ significantly among the clusters.
对两组患有先天性残疾、脑瘫和胎儿酒精综合征（FAS）儿童的母亲年龄进行了检查，并与一组先天性视神经发育不全（CONH）儿童的母亲进行了比较。CONH儿童的母亲年龄显著低于脑瘫儿童，而脑瘫儿童的母亲年龄又显著低于FAS儿童。此外，约一半的CONH儿童伴有其他残疾，这些残疾聚合成四种逐渐严重的组合。各组合之间母亲年龄和内分泌问题的发生率没有显著差异。
