Lipper E G, Voorhies T M, Ross G, Vannucci R C, Auld P A
Dev Med Child Neurol. 1986 Jun;28(3):303-9. doi: 10.1111/j.1469-8749.1986.tb03877.x.
This study attempted to identify within the first 48 hours of life those infants sustaining hypoxic-ischemic insults and destined to have neurodevelopmental abnormalities at one year of age. Neurological examination and cranial CT scan were quantitated to provide a post-asphyxia score and CT low-density index for each of 34 fullterm infants. The post-asphyxia score and CT infarction index were used to predict infants with normal and abnormal outcomes at one year of age, and both were valuable predictors of neurodevelopmental sequelae.
本研究试图在出生后48小时内识别出那些遭受缺氧缺血性损伤且在一岁时注定会出现神经发育异常的婴儿。对34名足月儿进行了神经学检查和头颅CT扫描定量分析,以得出每个婴儿的窒息后评分和CT低密度指数。窒息后评分和CT梗死指数用于预测一岁时结局正常和异常的婴儿,两者都是神经发育后遗症的重要预测指标。