Komorowski R A, Caya J G, Geenen J E
Gastrointest Endosc. 1986 Jun;32(3):190-2. doi: 10.1016/s0016-5107(86)71802-6.
The differential diagnosis of large gastric folds is diverse, and endoscopic biopsies are often too small to permit adequate morphologic evaluation. This article describes the morphology of large gastric folds obtained by electrosurgical endoscopic snare biopsy in a series of 52 patients. The great majority of patients with enlarged rugae presented with peptic ulcer symptoms. This series included 16 patients with hyperplastic gastropathies, 15 with chronic nonspecific gastritis, seven with gastric polyposis, three with adenocarcinoma, five with benign lymphoid hyperplasia, and the remainder with miscellaneous conditions. In all cases, the snare biopsy provided a full thickness mucosal biopsy adequate to fully evaluate the enlarged rugae.
胃大皱襞的鉴别诊断多种多样，而内镜活检组织往往过小，无法进行充分的形态学评估。本文描述了通过电外科内镜圈套器活检获取的52例患者胃大皱襞的形态。绝大多数皱襞增大的患者表现出消化性溃疡症状。该系列包括16例增生性胃病患者、15例慢性非特异性胃炎患者、7例胃息肉病患者、3例腺癌患者、5例良性淋巴组织增生患者，其余为其他杂症患者。在所有病例中，圈套器活检提供了全层黏膜活检，足以充分评估增大的皱襞。
