肿瘤微环境对铁死亡的影响：抑制还是促进
Effect of tumor microenvironment on ferroptosis: inhibition or promotion.
作者信息
Xia Zhengzhen, Quan Yi
机构信息
The First Clinical Medical School, Guangdong Medical University, Zhanjiang, Guangdong, China.
Department of Oncology Medical Center, The First People's Hospital of Zhaoqing, Zhaoqing, Guangdong, China.
出版信息
Front Oncol. 2023 May 5;13:1155511. doi: 10.3389/fonc.2023.1155511. eCollection 2023.
Ferroptosis is a type of lipid peroxidation-induced, iron-dependent programmed cell death. Emerging evidence suggests that ferroptosis is intimately connected to tumorigenesis, development, treatment and plays a major role in tumor immune regulation. This study focused on the connection between ferroptosis and immune regulation, which may offer a theoretical basis for targeting ferroptosis and tumor immunotherapy.
铁死亡是一种脂质过氧化诱导的、铁依赖性的程序性细胞死亡。新出现的证据表明，铁死亡与肿瘤发生、发展、治疗密切相关，并在肿瘤免疫调节中起主要作用。本研究聚焦于铁死亡与免疫调节之间的联系，这可能为靶向铁死亡和肿瘤免疫治疗提供理论基础。
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