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超低剂量计算机断层扫描在疑似社区获得性肺炎中的临床影响有限。

Limited Clinical Impact of Ultralow-Dose Computed Tomography in Suspected Community-Acquired Pneumonia.

作者信息

van Engelen Tjitske S R, Kanglie Maadrika M N P, van den Berk Inge A H, Altenburg Josje, Dijkgraaf Marcel G W, Bossuyt Patrick M M, Stoker Jaap, Prins Jan M

机构信息

Department of Internal Medicine, Division of Infectious Diseases, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, Netherlands.

Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, Netherlands.

出版信息

Open Forum Infect Dis. 2023 Apr 20;10(5):ofad215. doi: 10.1093/ofid/ofad215. eCollection 2023 May.

DOI:10.1093/ofid/ofad215
PMID:37213423
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10199111/
Abstract

Patients clinically suspected of community-acquired pneumonia (CAP) were randomized between ultralow-dose chest computed tomography ([ULDCT] 261 patients) and chest radiograph ([CXR] 231 patients). We did not find evidence that performing ULDCT instead of CXR affects antibiotic treatment policy or patient outcomes. However, in a subgroup of afebrile patients, there were more patients diagnosed with CAP in the ULDCT group (ULDCT, 106 of 608 patients; CXR, 71 of 654 patients; = .001).

摘要

临床上疑似社区获得性肺炎(CAP)的患者被随机分为两组,一组接受超低剂量胸部计算机断层扫描([ULDCT],261例患者),另一组接受胸部X光检查([CXR],231例患者)。我们没有发现证据表明用ULDCT代替CXR会影响抗生素治疗策略或患者预后。然而,在无发热的患者亚组中,ULDCT组诊断为CAP的患者更多(ULDCT组,608例患者中有106例;CXR组,654例患者中有71例;P = 0.001)。

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本文引用的文献

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2
Classifying the diagnosis of study participants in clinical trials: a structured and efficient approach.临床试验中研究参与者的诊断分类:一种结构化且高效的方法。
Eur Radiol Exp. 2020 Jul 17;4(1):44. doi: 10.1186/s41747-020-00169-y.
3
OPTimal IMAging strategy in patients suspected of non-traumatic pulmonary disease at the emergency department: chest X-ray or ultra-low-dose chest CT (OPTIMACT) trial-statistical analysis plan.疑似非创伤性肺部疾病的急诊科患者的 OPTimal IMAging 策略:胸部 X 射线或超低剂量胸部 CT(OPTIMACT)试验-统计分析计划。
Trials. 2020 May 14;21(1):407. doi: 10.1186/s13063-020-04343-w.
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Diagn Progn Res. 2018 Aug 8;2:20. doi: 10.1186/s41512-018-0038-1. eCollection 2018.
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