Suppr超能文献

脊髓硬脊膜脑脊液瘘作为自发性颅内低压综合征的病因:诊断与外科治疗

Spinal dural cerebrospinal fluid fistula as a cause of spontaneous intracranial hypotension syndrome: Diagnosis and surgical treatment.

作者信息

Konovalov Anton, Grebenev Fyodor, Asyutin Dmitry, Zakirov Bahromon, Konovalov Nikolay, Pronin Igor, Eliava Shalva, Chaurasia Bipin

机构信息

Burdenko Neurosurgical Center, Moscow, Russia.

Neurosurgery Clinic, Birgunj, Nepal.

出版信息

J Craniovertebr Junction Spine. 2023 Jan-Mar;14(1):108-112. doi: 10.4103/jcvjs.jcvjs_135_22. Epub 2023 Mar 13.

Abstract

Spontaneous intracranial hypotension (SIH) syndrome most often occurs following a cerebrospinal fluid (CSF) fistula that develops in the spinal space. Neurologists and neurosurgeons lack an understanding of the pathophysiology and diagnosis of this disease, which can make timely surgical care difficult. With the correct diagnostic algorithm, it is possible to identify the exact location of the liquor fistula in 90% of cases; subsequent microsurgical treatment can save the patient from the symptoms of intracranial hypotension and restore the ability to work. Female patient, 57 years old, was admitted with SIH syndrome. Magnetic resonance imaging (MRI) of the brain with contrast confirmed signs of intracranial hypotension. Computed tomography (CT) myelography was performed to pinpoint the location of the CSF fistula. The diagnostic algorithm and successful microsurgical treatment of a patient with spinal dural CSF fistula at the Th3-4 level using a posterolateral transdural approach. The patient was discharged on day 3 after the surgery when these complaints regressed completely. At the control examination of the patient 4 months postoperatively, there were no complaints. Identification of the cause and location of spinal the CSF fistula is a complex process that requires several stages of diagnosis. Examination of the entire back with MRI, CT myelography, or subtraction dynamic myelography is recommended. Microsurgical repair of a spinal fistula is an effective method for the treatment of SIH. The posterolateral transdural approach is effective in the repair of a spinal CSF fistula located ventrally in the thoracic spine.

摘要

自发性颅内低压(SIH)综合征最常发生在脊柱间隙出现脑脊液(CSF)瘘之后。神经科医生和神经外科医生对这种疾病的病理生理学和诊断缺乏了解,这可能导致难以及时进行手术治疗。采用正确的诊断算法,在90%的病例中能够确定脑脊液瘘的确切位置;随后的显微外科治疗可使患者摆脱颅内低压症状并恢复工作能力。57岁女性患者因SIH综合征入院。脑部增强磁共振成像(MRI)证实存在颅内低压迹象。进行了计算机断层扫描(CT)脊髓造影以确定脑脊液瘘的位置。采用后外侧经硬膜入路对一名Th3 - 4水平脊髓硬脊膜脑脊液瘘患者的诊断算法及成功的显微外科治疗。术后第3天,患者这些症状完全消退后出院。术后4个月对患者进行复查时,无任何不适主诉。确定脊髓脑脊液瘘的病因和位置是一个复杂的过程,需要多个诊断阶段。建议采用MRI、CT脊髓造影或减影动态脊髓造影对整个背部进行检查。脊髓瘘的显微外科修复是治疗SIH的有效方法。后外侧经硬膜入路对于修复位于胸椎腹侧的脊髓脑脊液瘘有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b95/10198209/ba4ebc5250b6/JCVJS-14-108-g001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验