Ghatge Sharad Balasaheb, Shah Rohit Pannalal, Surya Nirmal, Sankhala Suresh, Unadkat Chetan Jagjivandas, Khan Gulam M, Modi Dhaval B
Department of Radiology and Imaging, Division of Interventional Radiology, Grant Government Medical College and Sir JJ Group of Hospitals, Mumbai, Maharashtra, India.
Department of Interventional Neuroradiology, Bombay Hospital, Mumbai, Maharashtra, India.
J Craniovertebr Junction Spine. 2023 Jan-Mar;14(1):16-23. doi: 10.4103/jcvjs.jcvjs_141_22. Epub 2023 Mar 13.
Various minimally invasive surgeries were proposed for the management of herniated lumbar intervertebral disc. However, to choose optimal treatment modality to maximize patient benefit is a clinical challenge for the treatment givers.
The objective was to study the role of ozone disc nucleolysis in the management of herniated lumbar intervertebral disc by retrospective analysis.
We conducted a retrospective analysis of patients of lumbar disc herniation treated by ozone disc nucleolysis during May 2007-May 2021. There were total of 2089 patients with 58% of males and 42% of females. The age ranged from 18 to 88 years. Outcome was measured on the Visual Analog Scale (VAS) and the Oswestry Disability Index (ODI) along with modified MacNab method.
The mean baseline VAS score was 7.73, which became 3.07 at 1 month, 1.44 at 3 months, 1.42 at 6 months, and 1.36 at 1 year. Similarly, the mean ODI index was 35.92 at baseline, which improved to 9.17 at 1 month, 6.14 at 3 months, 6.10 at 6 months, and 6.09 at 1 year. VAS score and ODI analysis was found to be statistically significant with < 0.05. Modified MacNab criterion showed successful treatment outcome in 85.6% with excellent recovery in 1161 (55.58%), good recovery in 423 (20.25%), and fair recovery in 204 (9.77%). Mediocre or no recovery was seen in the remaining 301 patients amounting to a 14.40% failure rate.
This retrospective analysis confirms that ozone disc nucleolysis is an optimally effective and least invasive treatment option for herniated lumbar intervertebral disc with a significant reduction in disability.
针对腰椎间盘突出症的治疗，人们提出了各种微创手术方法。然而，选择最佳治疗方式以使患者受益最大化，这对治疗者来说是一项临床挑战。
通过回顾性分析，研究臭氧盘内溶核术在腰椎间盘突出症治疗中的作用。
我们对2007年5月至2021年5月期间接受臭氧盘内溶核术治疗的腰椎间盘突出症患者进行了回顾性分析。共有2089例患者，其中男性占58%，女性占42%。年龄范围为18至88岁。采用视觉模拟评分法（VAS）、Oswestry功能障碍指数（ODI）以及改良MacNab方法对治疗结果进行评估。
基线时VAS评分的平均值为7.73，1个月时降至3.07，3个月时为1.44，6个月时为1.42，1年时为1.36。同样，基线时ODI指数的平均值为35.92，1个月时改善至9.17，3个月时为6.14，6个月时为6.10，1年时为6.09。VAS评分和ODI分析具有统计学意义（<0.05）。改良MacNab标准显示，治疗成功率为85.6%，其中1161例（55.58%）恢复极佳，423例（20.25%）恢复良好，204例（9.77%）恢复尚可。其余301例患者恢复一般或未恢复，失败率为14.40%。
这项回顾性分析证实，臭氧盘内溶核术是治疗腰椎间盘突出症的一种最佳有效且微创的治疗选择，可显著降低残疾程度。
