Beck Eduard J, Mandalia Sundhiya, Yfantopoulos Platonas, Jones Christopher I, Bremner Stephen, Whetham Jennifer, Cunha Ana Sofia, Teofilo Eugenio, Rodrigues Goncalo, Borges Margarida
NPMS-HHC CIC, London, United Kingdom.
Department of Health Services Research and Policy, Faculty of Public Health & Policy, London School of Hygiene & Tropical Medicine, London, United Kingdom.
Porto Biomed J. 2022 Oct 24;7(5):e191. doi: 10.1097/j.pbj.0000000000000191. eCollection 2022 Sep-Oct.
The aim of this study was to calculate the cost-effectiveness of the EmERGE Pathway of Care for medically stable people living with HIV in the Hospital Capuchos, Centro Hospitalar Universitário de Lisboa Central (HC-CHLC). The app enables individuals to receive HIV treatment information and communicate with caregivers.
This before-and-after study collected the use of services data 1 year before implementation and after implementation of EmERGE from November 1, 2016, to October 30, 2019. Departmental unit costs were calculated and linked to mean use of outpatient services per patient-year (MPPY). Annual costs per patient-year were combined with primary (CD4 count; viral load) and secondary outcomes (PAM-13; PROQOL-HIV).
Five hundred eighty-six EmERGE participants used HIV outpatient services. Annual outpatient visits decreased by 35% from 3.1 MPPY (95% confidence interval [CI]: 3.0-3.3) to 2.0 (95% CI: 1.9-2.1) as did annual costs per patient-year from €301 (95% CI: €288-€316) to €193 (95% CI: €182-€204). Laboratory tests and costs increased by 2%, and radiology investigations decreased by 40% as did costs. Overall annual cost for HIV outpatient services decreased by 5% from €2093 (95% CI: €2071-€2112) to €1984 (95% CI: €1968-€2001); annual outpatient costs decreased from €12,069 (95% CI: €12,047-€12,088) to €11,960 (95% CI: €11,944-€11,977), with 83% of annual cost because of antiretroviral therapy (ART). Primary and secondary outcome measures did not differ substantially between periods.
The EmERGE Pathway produced cost savings after implementation-extended to all people living with HIV additional savings are likely to be produced, which can be used to address other needs. Antiretroviral drugs (ARVs) were the main cost drivers and more expensive in Portugal compared with ARV costs in the other EmERGE sites.
本研究旨在计算里斯本中央大学医院卡普乔斯医院(HC-CHLC)针对病情稳定的HIV感染者的EmERGE护理路径的成本效益。该应用程序使个人能够获取HIV治疗信息并与护理人员沟通。
这项前后对照研究收集了2016年11月1日至2019年10月30日实施EmERGE之前1年和之后的服务使用数据。计算部门单位成本并将其与每位患者每年门诊服务的平均使用量(MPPY)相关联。将每位患者每年的年度成本与主要结果(CD4细胞计数;病毒载量)和次要结果(PAM-13;PROQOL-HIV)相结合。
586名参与EmERGE项目的患者使用了HIV门诊服务。年度门诊就诊次数从3.1次MPPY(95%置信区间[CI]:3.0-3.3)降至2.0次(95%CI:1.9-2.1),降幅为35%,每位患者每年的年度成本也从301欧元(95%CI:288-316欧元)降至193欧元(95%CI:182-204欧元)。实验室检查及费用增加了2%,放射学检查次数及费用下降了40%。HIV门诊服务的总体年度成本从2093欧元(95%CI:2071-2112欧元)降至1984欧元(95%CI:1968-2001欧元),降幅为5%;年度门诊成本从12,069欧元(95%CI:12,047-12,088欧元)降至11,960欧元(95%CI:11,944-11,977欧元),其中83%的年度成本归因于抗逆转录病毒疗法(ART)。主要和次要结果指标在不同时期之间没有显著差异。
EmERGE护理路径实施后产生了成本节约——推广至所有HIV感染者可能会产生额外的节约,可用于满足其他需求。抗逆转录病毒药物(ARV)是主要的成本驱动因素,与其他EmERGE站点的ARV成本相比,葡萄牙的ARV成本更高。