Ganipineni Vijay Durga Pradeep, Gutlapalli Sai Dheeraj, Ajay Sai Krishna Kumar Idavalapati, Monica Potru, Vagdevi Moparthi, Samuel Sowrab Tamalapakula
Department of General Medicine, SRM Medical College Hospital and Research Center, Chennai, IND.
Department of General Medicine, Andhra Medical College/King George Hospital, Visakhapatnam, IND.
Cureus. 2023 Apr 20;15(4):e37880. doi: 10.7759/cureus.37880. eCollection 2023 Apr.
Based on the review of the literature, this article examines the potential therapeutic benefits of photobiomodulation therapy (PBMT) or low-level laser therapy (LLLT) for the treatment of cardiovascular disorders. The methodology involved searching PubMed, Google Scholar, and Central databases for relevant articles published from inception till date. The articles included in this review were preclinical and clinical studies investigating the effects of PBMT and LLLT on the heart. The article summarizes the findings of nineteen studies investigating the effects of PBMT and LLLT on various parameters related to heart failure (HF) and myocardial infarction (MI), including inflammation, oxidative stress, angiogenesis, cardiac function, and remodeling. The studies suggest that PBMT and LLLT have potential therapeutic benefits for the treatment of cardiovascular diseases and could be used in combination with traditional pharmacological therapies to enhance their effects or as a stand-alone treatment for patients who are not responsive to or cannot tolerate traditional therapies. In conclusion, this review article highlights the promising potential of PBMT for the treatment of HF and MI and the need for further research to fully understand its mechanisms of action and optimize treatment protocols.
基于文献综述，本文探讨了光生物调节疗法（PBMT）或低强度激光疗法（LLLT）治疗心血管疾病的潜在治疗益处。研究方法包括在PubMed、谷歌学术和中央数据库中检索从开始到目前发表的相关文章。本综述纳入的文章为研究PBMT和LLLT对心脏影响的临床前和临床研究。本文总结了19项研究的结果，这些研究调查了PBMT和LLLT对与心力衰竭（HF）和心肌梗死（MI）相关的各种参数的影响，包括炎症、氧化应激、血管生成、心脏功能和重塑。研究表明，PBMT和LLLT对心血管疾病的治疗具有潜在的治疗益处，可与传统药物疗法联合使用以增强其效果，或作为对传统疗法无反应或不耐受的患者的单独治疗方法。总之，这篇综述文章强调了PBMT治疗HF和MI的前景广阔，以及需要进一步研究以充分了解其作用机制并优化治疗方案。
