Calame J J, van't Wout J W, van Dijk J G, Bots G T
Histopathology. 1986 May;10(5):535-9. doi: 10.1111/j.1365-2559.1986.tb02504.x.
A case of Hodgkin's disease with eosinophilia in the cerebrospinal fluid without blood eosinophilia is presented. An additional remarkable feature was the finding of eosinophilia in Auerbach's myenteric plexus. Cerebrospinal fluid eosinophilia is usually associated with blood eosinophilia and this is often caused by helminthic infections of the CNS. The finding of cerebrospinal fluid eosinophilia without blood eosinophilia in any patient with Hodgkin's disease should point the physician to the possibility of a localization of tumour in the CNS.
本文报告一例霍奇金病患者，其脑脊液中出现嗜酸性粒细胞增多而外周血中嗜酸性粒细胞无增多。另一个显著特征是在奥尔巴赫肌间神经丛中发现嗜酸性粒细胞增多。脑脊液嗜酸性粒细胞增多通常与外周血嗜酸性粒细胞增多相关，且常由中枢神经系统的蠕虫感染引起。对于任何患有霍奇金病且脑脊液嗜酸性粒细胞增多而外周血嗜酸性粒细胞无增多的患者，医生应考虑肿瘤中枢神经系统定位的可能性。
