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组织学类型不同的同步双侧乳腺癌

Synchronous bilateral breast cancer with different histology.

作者信息

Al Marwani Marwan, Alamri Nasser, Allebdi Abdullah

机构信息

King Fahad Armed Forces Hospital, Al Kurnaysh Br Rd, Al Andalus, Jeddah 23311, Saudi Arabia.

出版信息

Radiol Case Rep. 2023 May 13;18(7):2491-2497. doi: 10.1016/j.radcr.2023.04.006. eCollection 2023 Jul.

DOI:10.1016/j.radcr.2023.04.006
PMID:37214322
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10196912/
Abstract

Synchronous bilateral breast cancer is a rare clinical entity. And due to both an improved prognosis and growing life expectancy on early detection, we have brought interest in case of patient with synchronous breast cancer. This study reports a case of synchronous bilateral breast cancer in an asymptomatic 70-year-old woman with a positive family history of breast cancer. This woman was diagnosed through radiological screenings, including mammograms, ultrasonography, and magnetic resonance imaging (MRI). On histopathologic examination of the core biopsy, the left breast mass was a Nottingham grade I invasive carcinoma of no particular type. The right breast mass was a Nottingham grade I invasive carcinoma with a mucinous component. After lumpectomies ultrasonography of the surgical specimens confirmed a small biopsy-proven invasive ductal cancer hypoechoic mass in the left breast, with an irregular margins and proven mucinous cancer mass in the right breast. The case was finally diagnosed as synchronous bilateral breast cancer of different pathologic types (ductal and mucinous).

摘要

同步双侧乳腺癌是一种罕见的临床实体。由于早期发现既能改善预后又能延长预期寿命,我们对同步乳腺癌患者产生了兴趣。本研究报告了一例70岁无症状女性同步双侧乳腺癌病例,该女性有乳腺癌家族史阳性。该女性通过包括乳房X线摄影、超声检查和磁共振成像(MRI)在内的放射学筛查被诊断出来。在对核心活检组织进行病理检查时,左乳肿块为诺丁汉I级非特殊类型浸润性癌。右乳肿块为伴有黏液成分的诺丁汉I级浸润性癌。在进行肿块切除术后,对手术标本的超声检查证实左乳有一个经活检证实的小的浸润性导管癌低回声肿块,边缘不规则,右乳有经证实的黏液癌肿块。该病例最终被诊断为不同病理类型(导管癌和黏液癌)的同步双侧乳腺癌。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/676b/10196912/88826d3ee9ff/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/676b/10196912/8ce472831004/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/676b/10196912/ca55c20914c2/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/676b/10196912/37e0b434c4dd/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/676b/10196912/88826d3ee9ff/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/676b/10196912/8ce472831004/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/676b/10196912/ca55c20914c2/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/676b/10196912/37e0b434c4dd/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/676b/10196912/88826d3ee9ff/gr4.jpg

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Synchronous and Metachronous Metastatic Breast Cancer, with Different Histology and Opposite Immunophenotype, Treated with Combination of Chemotherapy, Anti-Her2, and Endocrine Therapy: A Case Report.同步和异时性转移性乳腺癌,组织学不同且免疫表型相反,采用化疗、抗Her2和内分泌治疗联合方案治疗:一例报告
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