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1例蛛网膜下腔出血患者囊状脑动脉瘤自发性血栓形成的罕见病例。

A rare case of spontaneous thrombosis in saccular cerebral aneurysm in a patient with subarachnoid hemorrhage.

作者信息

Mahreni Ineke Rosalia, Sani Achmad Firdaus, Kurniawan Dedy

机构信息

Department Neurology, Faculty of Medicine, Airlangga University, - Dr. Soetomo General Hospital, Surabaya 60286, East Java, Indonesia.

出版信息

Radiol Case Rep. 2023 May 12;18(7):2470-2473. doi: 10.1016/j.radcr.2023.04.029. eCollection 2023 Jul.

Abstract

Cerebral aneurysm is a known cause of spontaneous subarachnoid hemorrhage (SAH). Furthermore, this condition is often asymptomatic, but the occurrence of a rupture can lead to fatal complications. The incidence of spontaneous thrombosis in saccular aneurysm is rare, with an incidence rate of 1%-2%. The most common sites include the middle cerebral artery (MCA) (41%), posterior communicating artery (PCOMM) (15%), and posterior inferior cerebellar artery (PICA) (11%). A head computed tomography angiography (CTA) with contrast is a common diagnostic tool for detecting SAH in the temporoparietal area, hippocampal gyrus, and right fissure of Sylvie. In some cases, saccular aneurysm can be found in the segment bifurcation of the right middle cerebral artery. A cerebral angiography was carried out, specifically digital subtraction angiography, which revealed the presence of visible blister remnants of aneurysm in the form of spontaneous thrombosis. After 1 year, another angiography evaluation was performed to assess the condition of the patient. Furthermore, the results showed no evidence of recanalization and there were no new neurologic deficits. Although spontaneous thrombosis led to the healing of aneurysm in some cases, secondary recanalization remained a possibility. Therefore, it was essential to monitor any incidence of this complication. Precise knowledge of the mechanism of spontaneous thrombosis could lead to the development of new therapeutic approaches. Spontaneous thrombosis in cases of saccular aneurysm is a rare occurrence, which can provide temporary or permanent benefits to the patient. Therefore, periodic evaluation is required to assess the condition of the patient.

摘要

脑动脉瘤是自发性蛛网膜下腔出血(SAH)的已知病因。此外,这种情况通常无症状,但破裂的发生可能导致致命并发症。囊状动脉瘤中自发性血栓形成的发生率很低,为1%-2%。最常见的部位包括大脑中动脉(MCA)(41%)、后交通动脉(PCOMM)(15%)和小脑后下动脉(PICA)(11%)。头颅计算机断层扫描血管造影(CTA)增强扫描是检测颞顶叶区域、海马回和大脑外侧裂右侧SAH的常用诊断工具。在某些情况下,可在右侧大脑中动脉节段分叉处发现囊状动脉瘤。进行了脑血管造影,具体为数字减影血管造影,结果显示存在以自发性血栓形式出现的可见动脉瘤泡状残余物。1年后,再次进行血管造影评估以评估患者状况。此外,结果显示没有再通迹象,也没有新的神经功能缺损。尽管自发性血栓形成在某些情况下可导致动脉瘤愈合,但仍有可能发生继发性再通。因此,监测这种并发症的任何发生率至关重要。对自发性血栓形成机制的精确了解可能会促成新治疗方法的开发。囊状动脉瘤病例中的自发性血栓形成很少见,可为患者带来暂时或永久的益处。因此,需要定期评估以评估患者状况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3db2/10196907/669d1402faf5/gr2.jpg

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