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人类高分辨率G带染色体的着丝粒指数和相对长度。

The centromere index and relative length of human high-resolution G-banded chromosomes.

作者信息

Van Dyke D L, Worsham M J, Fisher L J, Weiss L

出版信息

Hum Genet. 1986 Jun;73(2):130-2. doi: 10.1007/BF00291602.

DOI:10.1007/BF00291602
PMID:3721499
Abstract

The relative length and centromere index were compared in prometaphase and midmetaphase for each human chromosome from five normal men. There were very few differences between prometaphase and midmetaphase chromosomes in these two parameters. Chromosome 7 had a significantly different centromere index between prometaphase and midmetaphase, but no difference in relative length. This was accounted for by significant differences in the relative length of both 7p and 7q between prometaphase and midmetaphase; 7p became relatively less condensed and 7q relatively more condensed with progression from prometaphase to midmetaphase. For chromosome 1, the short arm was significantly longer than the long arm in both prometaphase and midmetaphase, a finding that underscores the structural similarity of this chromosome among the hominids.

摘要

对来自五名正常男性的每个人类染色体,在早中期和中期比较了其相对长度和着丝粒指数。在这两个参数上,早中期和中期染色体之间几乎没有差异。7号染色体在早中期和中期的着丝粒指数有显著差异,但相对长度没有差异。这是由于早中期和中期之间7p和7q的相对长度存在显著差异;随着从早中期发展到中期,7p相对变得不那么浓缩,而7q相对变得更浓缩。对于1号染色体,在早中期和中期,短臂都明显长于长臂,这一发现强调了该染色体在灵长类动物中的结构相似性。

相似文献

1
The centromere index and relative length of human high-resolution G-banded chromosomes.人类高分辨率G带染色体的着丝粒指数和相对长度。
Hum Genet. 1986 Jun;73(2):130-2. doi: 10.1007/BF00291602.
2
Delineation of human prometaphase paracentromeric regions using sequential GTG- and C-banding.
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The striking resemblance of high-resolution G-banded chromosomes of man and chimpanzee.人类和黑猩猩的高分辨率G带染色体惊人的相似性。
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Idiograms of horse chromosomes at prometaphase, early metaphase, and midmetaphase after R-banding by BrdU incorporation followed by the fluorochrome-photolysis-Giemsa technique.
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Differences in the localization and morphology of chromosomes in the human nucleus.人类细胞核中染色体定位和形态的差异。

本文引用的文献

1
An international system for human cytogenetic nomenclature--high-resolution banding (1981). ISCN (1981). Report of the Standing Committee on Human Cytogenetic Nomenclature.人类细胞遗传学命名国际系统——高分辨率显带(1981年)。《国际人类细胞遗传学命名法(1981年)》。人类细胞遗传学命名常务委员会报告。
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High-resolution ideograms of trypsin-Giemsa banded human chromosomes.胰蛋白酶 - 吉姆萨染色的人类染色体高分辨率 ideograms。 (注:ideograms 可能是特定语境下的术语,比如“核型模式图”等,具体含义需结合专业知识进一步确定准确中文表述)
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Immunocytochemical labelling of the kinetochore of human synaptonemal complexes, and the extent of pairing of the X and Y chromosomes.人类联会复合体动粒的免疫细胞化学标记以及X和Y染色体的配对程度。
Chromosoma. 1987;95(5):359-65. doi: 10.1007/BF00293183.
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Genetic markers on chromosome 7.7号染色体上的遗传标记。
J Med Genet. 1988 May;25(5):294-306. doi: 10.1136/jmg.25.5.294.
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The frequency of aneuploidy in cultured lymphocytes is correlated with age and gender but not with reproductive history.培养淋巴细胞中染色体数目异常的频率与年龄和性别相关,但与生殖史无关。
Am J Hum Genet. 1990 Jun;46(6):1101-11.
7
Parameters of the human genome.人类基因组参数。
Proc Natl Acad Sci U S A. 1991 Sep 1;88(17):7474-6. doi: 10.1073/pnas.88.17.7474.
中期人类染色体。达到2000条带纹。
Hum Genet. 1981;56(3):293-8. doi: 10.1007/BF00274682.
4
Chromosome 20 deletion in human multiple endocrine neoplasia types 2A and 2B: a double-blind study.人类2A型和2B型多发性内分泌腺瘤中20号染色体缺失:一项双盲研究。
Proc Natl Acad Sci U S A. 1984 Apr;81(8):2525-8. doi: 10.1073/pnas.81.8.2525.
5
High-resolution idiogram of Giemsa R-banded human prophase chromosomes.吉姆萨R带人类早前期染色体的高分辨率染色体模式图。
Can J Genet Cytol. 1983 Dec;25(6):642-50. doi: 10.1139/g83-095.
6
Analysis of human metaphase chromosome set by aid of DNA-binding fluorescent agents.借助DNA结合荧光剂对人类中期染色体组进行分析。
Exp Cell Res. 1970 Oct;62(2):490-2. doi: 10.1016/0014-4827(70)90586-0.
7
Analysis of the human karyotype using a reassociation technique.运用重缔合技术对人类染色体组型进行分析。
Chromosoma. 1971;34(4):448-54. doi: 10.1007/BF00326316.
8
Analysis of high-resolution R-bands, obtained by heat-denaturation and Giemsa staining, on human prophase chromosomes.对通过热变性和吉姆萨染色获得的人类前期染色体高分辨率R带进行分析。
Can J Genet Cytol. 1985 Feb;27(1):83-91. doi: 10.1139/g85-014.
9
Quantitative analysis of high-resolution trypsin-giemsa bands on human prometaphase chromosomes.人类前中期染色体上高分辨率胰蛋白酶-吉姆萨带的定量分析。
Hum Genet. 1978 Dec 18;45(2):137-65. doi: 10.1007/BF00286957.
10
G-banding patterns of high-resolution human chromosomes 6--22, X, and Y.高分辨率人类染色体6 - 22、X和Y的G带模式。
Hum Genet. 1979 Jul 18;49(3):291-306. doi: 10.1007/BF00569349.