Tsui L C
Department of Genetics, Hospital for Sick Children, Toronto, Ontario, Canada.
J Med Genet. 1988 May;25(5):294-306. doi: 10.1136/jmg.25.5.294.
Chromosome 7 is frequently associated with chromosome aberrations, rearrangements, and deletions. It also contains many important genes, gene families, and disease loci. This brief review attempts to summarise these and other interesting aspects of chromosome 7. With the rapid accumulation of cloned genes and polymorphic DNA fragments, this chromosome has become an excellent substrate for molecular genetic studies.
7号染色体常与染色体畸变、重排及缺失相关。它还包含许多重要基因、基因家族及疾病位点。本简要综述试图总结7号染色体的这些及其他有趣方面。随着克隆基因和多态性DNA片段的迅速积累,这条染色体已成为分子遗传学研究的优良对象。