Ohashi T, Kase M, Yokoi M
Invest Ophthalmol Vis Sci. 1986 Jul;27(7):1160-4.
The oculocardiac reflex was quantitatively studied in 15 patients with strabismus. The reflex was observed in all patients when the medial rectus and inferior oblique muscles were stretched; the medial rectus muscle had a lower threshold than the inferior oblique. Bradycardia was evoked in 7 of the 15 patients when the lateral rectus was tractioned with tensions of 50 g and 600 g. The oculocardiac reflex was a graded phenomenon as a function of tension applied to the extraocular muscles. As tension was increased, bradycardia occurred rapidly and became deep. Systemic administration of atropine prevented completely the bradycardia from occurring. The results suggest that the response of the extraocular muscles to stretch are critically mediated through a polysynaptic path to the heart, resulting in suppression of the heart rate.
对15例斜视患者的眼心反射进行了定量研究。当牵拉内直肌和下斜肌时，所有患者均观察到该反射；内直肌的阈值低于下斜肌。当以50克和600克的张力牵拉外直肌时，15例患者中有7例出现心动过缓。眼心反射是一种与施加于眼外肌的张力相关的分级现象。随着张力增加，心动过缓迅速出现且程度加深。全身给予阿托品可完全防止心动过缓的发生。结果表明，眼外肌对牵拉的反应是通过一条多突触路径严重介导至心脏，从而导致心率抑制。
