Center for Cardiovascular Research and Heart Center, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.
Department of Pediatrics, The Ohio State University College of Medicine, Columbus, Ohio, USA.
Birth Defects Res. 2023 Jun 1;115(10):959-966. doi: 10.1002/bdr2.2186. Epub 2023 May 22.
The Society for Birth Defects Research and Prevention (BDRP) strives to understand and protect against potential hazards to developing embryos, fetuses, children, and adults by bringing together scientific knowledge from diverse fields. The theme of 62nd Annual Meeting of BDRP, "From Bench to Bedside and Back Again", represented the cutting-edge research areas of high relevance to public health and significance in the fields of birth defects research and surveillance. The multidisciplinary Research Needs Workshop (RNW) convened at the Annual Meeting continues to identify pressing knowledge gaps and encourage interdisciplinary research initiatives. The multidisciplinary RNW was first introduced at the 2018 annual meeting to provide an opportunity for annual meeting attendees to participate in breakout discussions on emerging topics in birth defects research and to foster collaboration between basic researchers, clinicians, epidemiologists, drug developers, industry partners, funding agencies, and regulators to discuss state-of-the-art methods and innovative projects. Initially, a list of workshop topics was compiled by the RNW planning committee and circulated among the members of BDRP to obtain the most popular topics for the Workshop discussions. Based on the pre-meeting survey results, the top three discussion topics selected were, A) Inclusion of pregnant and lactating women in clinical trials. When, why, and how? B) Building multidisciplinary teams across disciplines: What cross-training is needed? And C) Challenges in applications of Artificial Intelligence (AI) and machine learning for risk factor analysis in birth defects research. This report summarizes the key highlights of the RNW workshop and specific topic discussions.
生育缺陷研究与预防学会（BDRP）致力于通过汇集来自不同领域的科学知识，来了解和防范潜在的胚胎、胎儿、儿童和成人发育危害。BDRP 第 62 届年会的主题为“从基础到临床再到基础”，代表了与公共卫生高度相关且在生育缺陷研究和监测领域具有重要意义的前沿研究领域。在年会上召开的多学科研究需求研讨会（RNW）继续确定紧迫的知识差距，并鼓励开展跨学科研究计划。该多学科 RNW 于 2018 年的年会上首次推出，为年会与会者提供了一个参与生育缺陷研究新兴主题分组讨论的机会，并促进了基础研究人员、临床医生、流行病学家、药物开发者、行业合作伙伴、资助机构和监管机构之间的合作，以讨论最先进的方法和创新项目。最初，研讨会主题清单由 RNW 规划委员会编制，并在 BDRP 成员中传阅，以获取研讨会讨论的最受欢迎主题。根据会前调查结果，选定的三个讨论主题是：A）将孕妇和哺乳期妇女纳入临床试验。何时、为何以及如何纳入？B）跨学科建立多学科团队：需要哪些交叉培训？C）在生育缺陷研究的风险因素分析中应用人工智能（AI）和机器学习的挑战。本报告总结了 RNW 研讨会和特定主题讨论的要点。
