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食管切除和胃上提术后吻合口漏的处理。

Management of anastomotic leaks after oesophagectomy and gastric pull-up.

出版信息

Bratisl Lek Listy. 2023;124(7):508-512. doi: 10.4149/BLL_2023_078.

Abstract

OBJECTIVE

To evaluate the effectiveness of endoscopic and surgical intervention in treating anastomotic leaks after oesophagectomy.

BACKGROUND

Anastomotic leak after oesophagectomy is a severe complication associated with significant morbidity and mortality. This study aimed to analyse our experience with the management of anastomotic leak after oesophagectomy.

METHODS

A retrospective study evaluated the treatment outcome and duration of treatment in patients with anastomotic dehiscence or conduit necrosis after oesophagectomy from November 2008 to November 2021.

RESULTS

The group consists of forty-seven patients. Twenty-one (44.7 %) patients had dehiscence of the neck anastomosis, twenty patients (42.6 %) had dehiscence of the chest anastomosis, and six (12.8 %) patients had conduit necrosis. Nineteen patients with dehiscence were primarily treated by endoscopic insertion of a self-expanding metal stent with perianastomotic drainage; the other patients were primarily treated surgically. Mortality associated with anastomosis dehiscence was 27.7 % (thirteen patients). Stent use in treatment was a statistically significant parameter regarding the length of hospital stay and mortality.

CONCLUSION

Self-expanding metal stents can reduce leak-related morbidity and mortality after oesophagectomy and may be considered a cost-effective treatment alternative (Tab. 2, Fig. 2, Ref. 21).

摘要

目的

评估内镜和手术干预治疗食管切除术后吻合口漏的效果。

背景

食管切除术后吻合口漏是一种严重的并发症,与较高的发病率和死亡率相关。本研究旨在分析我们在食管切除术后吻合口漏管理方面的经验。

方法

回顾性研究分析了 2008 年 11 月至 2021 年 11 月间食管切除术后吻合口裂开或移植物坏死患者的治疗结果和治疗持续时间。

结果

该组包括 47 例患者。21 例(44.7%)患者出现颈部吻合口裂开,20 例(42.6%)患者出现胸腔吻合口裂开,6 例(12.8%)患者出现移植物坏死。19 例吻合口裂开患者主要通过内镜插入自膨式金属支架和吻合口周围引流进行治疗;其他患者主要通过手术治疗。吻合口裂开相关死亡率为 27.7%(13 例)。支架使用在治疗中是与住院时间和死亡率相关的统计学显著参数。

结论

自膨式金属支架可降低食管切除术后与漏相关的发病率和死亡率,并且可能是一种具有成本效益的治疗选择(表 2,图 2,参考文献 21)。

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